Houston Astros vs. Los Angeles Angels Picks and Prediction for Sunday, September 28, 2025
Use Code SSWC Our Astros vs. Angels prediction sees the Houston Astros (85-75) getting ready to take on the Los Angeles Angels (72-88) in American League West action at Angel Stadium on Sunday afternoon to end the season. This article is being written ahead of Saturday’s game. Right-hander Cristian Javier gets the start for the Astros while rookie southpaw Sam Aldegheri pitches for the Angels. From splits to bullpens, MLB predictions for the Houston Astros vs. the Los Angeles Angels highlight the edge.
Astros Not Making the Playoffs
The Houston Astros are looking to bounce back after their 4-3 road loss on Friday against the Los Angeles Angels. The lineup was able to go 6-for-35 with one walk and 13 strikeouts as Christian Walker hit a home run while Ramon Urias and Zach Cole each stole a base. The Astros were only 1-for-9 with runners in scoring position and stranded six men on base. Jason Alexander did okay in this game as he allowed two runs in 4.2 innings while not factoring into the decision.
Right-hander Cristian Javier is going to toe the slab for the Houston Astros and has only made eight starts this season. He is 2-4 with a 4.62 ERA and a 1.27 WHIP in 37.0 innings of work. He has been limited to the amount of home runs as he has allowed three entering this start. Javier faced the Angels once this season without factoring into the decision, as he threw six no-hit innings as he giving up three walks and six strikeouts.
Injury Report for Houston
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- Center fielder Jake Meyers: Calf (Questionable)
- Shortstop Jeremy Pena: Oblique (Questionable)
- Left fielder Yordan Alvarez: Ankle (OUT)
- Pitcher Kaleb Ort: Elbow (OUT)
- Pitcher Lance McCullers Jr: Hand (OUT)
- Pitcher Luis Garcia: Elbow (OUT)
- Pitcher Spencer Arrighetti: Elbow (OUT)
- Pitcher John Rooney: Concussion/Nasal (OUT)
Angels Looking to End with a Win
The Los Angeles Angels are coming off a 4-3 home win on Friday against the Houston Astros in their most recent outing. The team was able to go 8-for-29 with three walks and four strikeouts as Mike Trout hit a pair of homers. The Angels were 2-for-5 with runners in scoring position and left four men on base. Kyle Hendricks did not factor into the decision as he pitched five innings and gave up three runs (two earned).
The Angels are going to be sending rookie left-hander Sam Aldegheri to the mound, and he is currently 0-1 with an 8.00 ERA and a 2.22 WHIP in 9.0 innings. He has struggled to keep hitters off base as he has a .342 batting average against up to this point. Aldegheri faced the Astros once last season in a loss as in two innings he allowed four runs on six hits with five walks and zero strikeouts.
Injury Report for Athletics
- Pitcher Yusei Kikuchi: Forearm (Questionable)
- Pitcher Robert Stephenson: Elbow (OUT)
- Pitcher Joel Soriano: Ribs (OUT)
- Shortstop Zach Neto: Hand (OUT)
- Catcher Travis d’Arnaud: Head (OUT)
- Pitcher Andrew Chafin: Triceps (OUT)
Houston Astros vs. Los Angeles Angels Pick
Spread Pick for Astros vs. Angels
- Houston Astros ML (5 units)
Cristian Javier is struggling since returning from injury, but Sam Aldegheri has been struggling in the majors so far. The Angels have the better overall roster and should be in a better position to be successful in Game 162, as they have the better pitcher and lineup. All in all, go with the Houston Astros to win.
Over/Under Pick for Astros vs. Angels
- Under (4 units)
These teams understand this game is meaningless, so do not expect many runs to be scored. Neither team is competing for a postseason appearance as they have both been officially eliminated from that. Neither team has done too well against the other starting pitcher either, leaving the chance for these pitchers to end the season strong. The under hit in four of the previous five games between the Astros and the Angels, so go with the under once again to hit.
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