Houston Astros vs Toronto Blue Jays Picks and Prediction for Tuesday, September 9, 2025
The Houston Astros (78-66, 65-71-8 O/U) will be taking on the Toronto Blue Jays (82-61, 80-57-6 O/U) on Wednesday evening in the opening game of a three-game American League series for our Astros vs. Blue Jays prediction. Both teams were off on Monday so they should be rested for this game. Right-hander Luis Garcia (1-0, 4.50 ERA) is going to be pitching in this game for the Astros, while the Blue Jays are sending righty Jose Berrios (9-5, 4.02 ERA) to the hill. From splits to bullpens, MLB predictions for Houston Astros vs Toronto Blue Jays that cut through the noise.
Astros Trying to Hold Onto AL West Lead
The Houston Astros are doing a solid job as they are first in the AL West with a 78-66 record up to this point. The Astros are hitting at a brutal level as they are 28th in the bigs with a .676 team OPS while averaging 4.23 runs per game.
The Houston Astros are coming off a 4-2 road loss on Sunday to the Texas Rangers and it does not help going 1-for-6 with runners in scoring position. Framber Valdez recorded the loss as he allowed four runs (three earned) in seven innings.
Shortstop Jeremy Pena (.833 OPS, 20 SB) has been clicking at the plate and continues to be a threat on the bases as well. Rookie right-hander Yoendrys Gomez (1-0, 4.50 ERA) will be taking the mound and won his 2025 debut as he pitched six innings and allowed three runs on three hits with zero walks and six strikeouts against the Los Angeles Angels.
Injury Report for Houston
- Pitcher Kaleb Ort: Elbow (OUT)
- Pitcher Spencer Arrighetti: Elbow (OUT)
- Pitcher John Rooney: Concussion/Nasal (OUT)
- Pitcher Bennett Sousa: Elbow (OUT)
- Pitcher Brandon Walter: Elbow (OUT)
- Pitcher Josh Hader: Shoulder (OUT)
- Third baseman Isaac Paredes: Hamstring (OUT)
- Right fielder Zach Dezenzo: Hand (OUT)
- Right fielder Pedro Leon: Knee (OUT)
- Pitcher Ronel Blanco: Elbow (OUT)
- Pitcher Hayden Wesneski: Elbow (OUT)
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Blue Jays Looking to Hang Onto AL East Lead
The Toronto Blue Jays are looking to continue winning games as they are first in the AL East with an 82-61 record up to this point. The offense is on fire as they are second in baseball with a .269/.338/.433 team slash line while averaging 5.0 runs per game.
The Toronto Blue Jays are coming off a 4-3 road loss on Sunday to the New York Yankees and it does not help being 2-for-12 with runners in scoring position. Max Scherzer struggled in a losing effort as he allowed four runs in 4.1 innings in a losing effort.
Designated hitter George Springer (27 HR, 16 SB) has been clicking at the plate and could step up with a 20-20 season. Right-hander Jose Berrios (9-5, 4.02 ERA) is going to be on the mound and is coming off a no-decision against the Cincinnati Reds, where he allowed six runs (two earned) on five hits with two walks and two strikeouts.
Injury Report for Toronto
- Pitcher Robinson Pina: Elbow (OUT)
- Pitcher Nick Sandlin: Elbow (OUT)
- Pitcher Yimi Garcia: Ankle (OUT)
- Pitcher Bowden Francis: Shoulder (OUT)
- Pitcher Ryan Burr: Shoulder (OUT)
- Right fielder Anthony Santander: Shoulder (OUT)
- Pitcher Alek Manoah: Elbow (OUT)
- Pitcher Angel Bastardo: Elbow (OUT)
Houston Astros vs. Toronto Blue Jays Pick
Spread Pick for Houston Astros vs. Toronto Blue Jays
- Houston Astros ML (4 units)
Since the All-Star break, these teams are pitching at a similar level, as Houston is 20th with a 4.34 team ERA, while Toronto is 22nd with a 4.42 team ERA right now. Both pitching staffs have been able to dominate when facing runners in scoring position. The Astros are best in baseball with a .223 batting average against in those positions while the Blue Jays are fourth (second in AL) with a .238 opposing batting average with runners in scoring position. The Astros won the previous five games against the Blue Jays so go with the Houston Astros to secure the victory.
Over/Under Pick for Houston Astros vs. Toronto Blue Jays
- Under (4 units)
These bullpens are doing well over the course of the season as Houston is eighth with a 3.71 reliever ERA, while Toronto is 16th with a 4.10 bullpen ERA right now. The offenses are the two worst in terms of hitting into double plays as the Astros are 29th with 113 double plays hit int,o while the Blue Jays are 30th with 118 double plays hit into thus far. The under hit all three games against one another this season so let’s take the under here once again.
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