Houston Astros vs Toronto Blue Jays Picks and Prediction for Wednesday June 24 2026

By: Kim Smith Published 06/24/2026, 01:00 AM ET
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The Houston Astros and Toronto Blue Jays meet on Wednesday, June 24, 2026, at Rogers Centre in Toronto, Ontario. First pitch is scheduled for 7:07 PM ET, with coverage available on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Houston is expected to start Mike Burrows in this matchup. Burrows enters with a 3-8 record, a 5.79 ERA, and a 1.58 WHIP across 79.1 innings. He has allowed 95 hits, struck out 66 batters, walked 30, and surrendered 18 home runs. Toronto is scheduled to counter with Trey Yesavage, who comes into the game with a 3-3 record, a 3.76 ERA, and a 1.16 WHIP over 55.0 innings. He has allowed 39 hits, recorded 53 strikeouts, issued 25 walks, and given up five home runs.

Houston Tries to Recover After Series Opener

The Astros enter this contest with a 37-43 overall record and a 17-22 road record. Houston has gone 3-2 over its last five games. The Astros recently defeated Cleveland twice and Detroit while suffering losses to Toronto and Cleveland during that stretch.

Houston is batting .242 as a team with 358 runs scored, 650 hits, and 103 home runs. The Astros own a .317 on-base percentage and a .410 slugging percentage. On the pitching side, they have posted a 4.84 ERA and a 1.41 WHIP while recording 689 strikeouts. Opponents are batting .243 against Houston. The Astros are also 15-16 in day games.

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The biggest strength for Houston is its power production. The Astros have hit 103 home runs this season, significantly more than Toronto’s 78. They have also scored more runs and posted a higher slugging percentage, giving them the ability to generate offense quickly when opportunities arise.

Toronto Looking to Build Momentum

The Blue Jays come into this matchup with a 39-39 overall record and a 22-18 home record. Toronto has won four of its last five games and enters after victories over Houston, Chicago twice, and Boston twice. Their lone loss during that stretch came against Chicago.

Toronto is hitting .250 as a team with 320 runs scored, 654 hits, and 78 home runs. The Blue Jays have produced a .313 on-base percentage and a .393 slugging percentage. Their pitching staff owns a 4.10 ERA and a 1.30 WHIP while recording 686 strikeouts. Opponents are batting .241 against Toronto. The Blue Jays are also 17-17 in day games.

The strength of Toronto has been its overall balance. The Blue Jays own the better batting average, lower ERA, lower WHIP, and lower opponent batting average. Those advantages have helped them climb back to the .500 mark and put together a strong recent stretch.

Houston Astros vs Toronto Blue Jays Picks and Prediction

Houston Astros vs Toronto Blue Jays Pick

  • Pick: Toronto Blue Jays Moneyline

Toronto enters this game with the better recent form, having won four of its last five contests. The Blue Jays also hold advantages in ERA, WHIP, opponent batting average, and the projected starting pitching matchup. The matchup predictor gives Toronto a sizable edge as well. While Houston has more power, Toronto’s stronger pitching profile makes the Blue Jays the preferred side.

Houston Astros vs Toronto Blue Jays Total Pick

  • Take the over if the total is set at 8.5.

I would lean toward the over if the number is set at 8.5. Houston has already hit 103 home runs this season and scored 358 runs, while Toronto enters with a hot offense that has won four of its last five games. Houston’s pitching staff carries a 4.84 ERA, and the Astros’ projected starter enters with a 5.79 ERA. Those numbers point toward scoring opportunities for both teams.

Final Score Prediction: Toronto Blue Jays 6 – Houston Astros 4

This prediction was written before the completion of game play on Tuesday.

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