Houston Astros vs Washington Nationals Picks and Prediction for Monday, July 6, 2026

By: Kim Smith Published 07/06/2026, 12:10 AM ET
Use Code SSWC

The Houston Astros and Washington Nationals begin a new series on Monday, July 6, 2026, at Nationals Park in Washington, District of Columbia. First pitch is scheduled for 6:45 PM with coverage available on MLB.TV. Washington enters as a -137 moneyline favorite, while Houston is listed at +114. The run line has the Astros at +1.5 (-171) and the Nationals at -1.5 (+141). The total is set at 10 runs. Be sure to check out our free MLB picks for even more baseball predictions and betting analysis.

Starting Pitchers Set for Monday's Matchup

Houston is expected to start Mike Burrows, who enters with a 4-8 record, a 5.58 ERA, and a 1.51 WHIP over 90.1 innings. He has allowed 103 hits while striking out 72 batters, walking 33, and giving up 19 home runs. Washington is scheduled to counter with Miles Mikolas, who owns a 2-7 record with a 5.44 ERA and a 1.29 WHIP across 84.1 innings. Mikolas has surrendered 92 hits while recording 47 strikeouts, issuing 17 walks, and allowing 18 home runs.

Houston Looks to Carry Momentum on the Road

The Astros head into this contest with a 45-47 overall record and a 22-23 mark away from home. Houston has won three of its last five games, including back-to-back victories over Tampa Bay after splitting the previous three contests with losses to Minnesota and a win over the same opponent. The recent stretch has helped the Astros build some momentum entering this road series.

Houston has posted a .242 team batting average while scoring 411 runs on 739 hits this season. The club has connected for 120 home runs with a .316 on-base percentage and a .410 slugging percentage. On the mound, the Astros own a 4.78 ERA and a 1.39 WHIP while holding opponents to a .240 batting average. Their pitching staff has also recorded 786 strikeouts against 395 walks.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that StatSalt may use third-party services to process my data.

One of Houston's biggest advantages is its ability to generate power at the plate. The Astros have hit 120 home runs, nearly matching Washington's offensive production while pairing that with a lower opponent batting average. If they continue producing timely offense, they have an opportunity to remain competitive despite entering with a record below .500.

Washington Tries to Defend Home Field

Washington enters Monday with a 46-45 overall record and an 18-27 record at Nationals Park. The Nationals have won three of their last five games after earning victories over both Pittsburgh and Boston, although they are also coming off consecutive losses to Pittsburgh in their most recent contests.

The Nationals have been productive offensively, batting .248 as a team while scoring 480 runs on 766 hits. They have hit 123 home runs while posting a .322 on-base percentage and a .429 slugging percentage. Their pitching staff carries a 4.66 ERA with a 1.39 WHIP and has limited opponents to a .258 batting average. Washington pitchers have totaled 710 strikeouts while issuing 314 walks.

The biggest strength for Washington has been its offense. The Nationals hold the advantage in batting average, runs scored, hits, home runs, on-base percentage, and slugging percentage. Those numbers have allowed them to consistently generate scoring opportunities, making their lineup the foundation of their success this season.

Houston Astros vs Washington Nationals Picks and Prediction

Houston Astros vs Washington Nationals Pick

  • Pick: Nationals Moneyline (-137)

Washington owns the better overall record and has been the more productive offensive team across nearly every major category provided. The Nationals have scored more runs, collected more hits, and produced slightly more power than Houston. While both projected starters have similar ERAs, I like Washington's stronger offensive profile to make the difference at home.

Houston Astros vs Washington Nationals Total Pick

  • Pick: Over 10

I'm taking the over 10 in this matchup. Both starting pitchers enter with ERAs above 5.40, and both teams have surpassed 120 home runs this season. Washington has scored 480 runs, while Houston has also shown solid power production. With those numbers, I see enough offensive potential for this game to reach the posted total.

Final Score Prediction: Washington Nationals 7 – Houston Astros 5

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Review
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Review
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
Fanatics

10 x $100 bet match in FanCash

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Fanatics Review
Cashable No
>

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.