Kansas City Royals vs. Athletics Picks and Predictions, Saturday September 27, 2025

By: Nathan Smith Published 09/27/2025, 09:49 AM ET
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The Major League Baseball season has all but reached its conclusion, and while there are teams out of playoff contention, it doesn't mean the games mean less, as we'll see in our Kansas City Royals vs. Athletics prediction.

The Kansas City Royals (80-80) came into 2025 with very high expectations, and while they're going to fall short of their postseason, their fight late in the season holds them in good standing for years to come.

On Saturday , they battle the Athletics (76-84), a team that has shown flashes of greatness due to their young core, and with a strong finish, they could lead themselves into a massive winger. Read on to see our Kansas City Royals vs. Athletics prediction.

Expected pitching matchup: RHP Michael Wacha vs. RHP Luis Morales.

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Can the Royals finish 2025 over .500?

The Kansas City Royals took a huge step forward in 2025, and while they didn't quite get the career years this season from some players, they showed that they can consistently compete at the top level despite a 37-42 record away from home. Despite having a superstar like Bobby Witt Jr. leading the way, the Royals rank 26th in baseball in total runs scored, but with a 3.75 team ERA ranking them sixth in the league, they've got some major building blocks in place already.

In this one, Kansas City turns to veteran right-hander Michael Wacha, who has compiled a solid 4.00 ERA across 30 starts this season, with the 30-year-old tossing 160 or more innings in 2025 for the second straight season. Last time out for the Royals was a tight loss to these Athletics, with three RBI to Jonathan India representing the entire offensive output on the night as Noah Cameron allowed three runs over 4.1 innings of work as they came up short 4-3.

Can the Athletics finish 2025 full of momentum?

The Athletics have struggled to put together any success in recent years, but with the young core led by Nick Kurtz, Jacob Wilson and others, they remained fairly competitive this season, even if they are currently seven games under .500 at home. This Athletics season has been all about their offense, as they rank sixth in the league in batting average and 12th in runs scored, giving them plenty of optimism as they look to handle their current organizational transition.

Taking the mound for the A's here will be rookie right-hander Luis Morales, who has a 3.07 ERA across his first nine career appearances, with the 23-year old striking out a solid 38 hitters across 44.0 innings of work in that time. Last time out for the Athletics was a great win over these Royals, with Mason Barnett giving a solid 5.2 innings of three-run ball as as three RBI to Jacob Wilson helped lead them to a 4-3 win.

Kansas City Royals vs. Athletics pick

Money line pick for Royals vs. Athletics

  • Athletics -115 (4 units)

After the victory in game one of this series, the Athletics have now won three straight contests against the Royals, with the head-to-head record in their last 10 matchups now sitting at 6-4 in favor of the home team here.

In that time, the A's are now 3-1 in their last four games played at home, and with a young, up-start rookie leading a very talented lineup, expect the Athletics to come away with a victory in this one.

Over/Under pick for Royals vs. Athletics

  • Under 10 (4 units)

Despite the fact that the offense of the A's is one of the best in the league, these two teams have played some low-scoring games in recent times, with the under being 7-3 in their last 10 head-to-head encounters, with seven or less total runs scored in three of their four games played in 2025.

For the Royals, the under sits at 4-6 in their last 10 overall games, with four or less runs allowed in six of those games, and for the Athletics, the under comes in at 6-3-1 in their past 10, with four or less allowed on seven occasions in that span.

Keep it simple, take the under.

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