Los Angeles Angels vs Boston Red Sox Picks and Prediction for Wednesday September 9 2026

The Los Angeles Angels and Boston Red Sox meet at Fenway Park in Boston, Massachusetts, on Wednesday, September 9, 2026. First pitch is scheduled for 6:45 PM ET with coverage on MLB.TV. Los Angeles enters the matchup at 54-90 overall and 24-46 on the road, while Boston is 80-65 overall and 36-34 at home. The Red Sox won the opening game of the series 5-2 and enter this matchup riding a five-game winning streak. At the time of this writing the odds were not released. Be sure to check out our free MLB picks throughout the season.

Starting Pitchers

Los Angeles is scheduled to start Ryan Johnson, who enters at 3-8 with a 5.17 ERA and 1.39 WHIP across 78.1 innings. He has allowed 71 hits and 38 walks while striking out 58 and surrendering 16 home runs. Boston counters with Jake Bennett, who is 9-6 with a 3.34 ERA and 1.02 WHIP through 99.2 innings. He has allowed 84 hits and only 18 walks while recording 81 strikeouts and allowing nine home runs. Boston owns a considerable statistical advantage in the starting matchup, with the better ERA, WHIP, strikeout production and home-run prevention.

Los Angeles Continues to Struggle on the Road

The Angels enter Wednesday at 54-90 overall and just 24-46 away from home. Los Angeles has lost four of its last five games, including a 5-2 defeat against Boston in the opening game of this series. The Angels also dropped two of three on the road against Pittsburgh, with both losses coming by identical 1-0 scores. Their lone victory over the last five games was a 6-1 win.

Los Angeles is batting .233 with 579 runs, 1,121 hits and 137 home runs. The Angels have produced a .307 on-base percentage and .369 slugging percentage. Their pitching staff owns a 4.22 ERA and 1.34 WHIP while allowing opponents to bat .236. The staff has issued 582 walks and recorded 1,283 strikeouts.

The biggest concern for Los Angeles is an offense that has repeatedly failed to provide enough scoring support. The Angels have produced only nine runs across their last five games and have been held to one run or fewer three times during that stretch. Their .233 batting average and .369 slugging percentage also trail Boston by substantial margins, while Wednesday's starting pitching matchup gives the Angels another difficult obstacle to overcome.

Boston Carries a Five-Game Winning Streak

Boston enters this matchup at 80-65 overall and 36-34 at Fenway Park. The Red Sox are playing their best baseball of the recent stretch, winning five consecutive games. Boston opened this series with a 5-2 victory and swept its previous four-game road series with wins of 6-5, 1-0, 5-0 and 3-1. The Red Sox have allowed only eight total runs during their five-game winning streak.

The Red Sox are batting .249 with 647 runs, 1,211 hits and 151 home runs. Boston has a .323 on-base percentage and .406 slugging percentage. Its pitching staff has been one of the stronger components of the club, producing a 3.59 ERA and 1.23 WHIP. Opponents are batting .241, while the staff has issued 418 walks and recorded 1,251 strikeouts.

Boston holds a clear statistical advantage across most of the important categories in this matchup. The Red Sox have scored 68 more runs than Los Angeles while posting the better batting average, on-base percentage and slugging percentage. Their 3.59 team ERA is also considerably better than the Angels' 4.22 mark, and Boston has issued 164 fewer walks. Combine those season-long advantages with a five-game winning streak and the stronger scheduled starter, and Boston enters Wednesday in the better overall position.

Los Angeles Angels vs Boston Red Sox Picks and Prediction

Pick: Boston Red Sox Moneyline

Boston is the preferred side in a matchup where most of the available numbers point toward the home team. The Red Sox have the superior record, are riding a five-game winning streak and have significant advantages in batting average, on-base percentage, slugging percentage and team ERA. Los Angeles is only 24-46 on the road and has scored just nine runs over its last five games. Boston also owns a substantial starting pitching advantage based on the supplied numbers. Back the Boston Red Sox moneyline on Wednesday.

Pick: Under 8.5

The recent scoring numbers make the Under 8.5 the preferred total if the market reaches 8.5 or higher. Los Angeles has been held to two runs or fewer in four of its last five games, including two shutout losses, while Boston has allowed only eight runs during its five-game winning streak. Boston's scheduled starter brings a 3.34 ERA and 1.02 WHIP into the matchup, which creates another difficult assignment for an Angels offense batting .233. Los Angeles' pitching matchup creates some risk, but Boston may not need a huge offensive output to control this game. Take the Under if the total is set at 8.5 or higher.

Final Picks: Boston Red Sox Moneyline and Under 8.5

This preview was completed before play on Tuesday. Starting pitchers, betting lines and other game information are subject to change before the game begins.