Los Angeles Dodgers vs Philadelphia Phillies Picks and Prediction for Wednesday, July 22, 2026
The Los Angeles Dodgers visit the Philadelphia Phillies at Citizens Bank Park in Philadelphia, Pennsylvania, on Wednesday, July 22, 2026. The game is scheduled for 6:40 p.m. ET, with television coverage available on MLB.TV and two additional options. Los Angeles enters with a 63-38 overall record, while Philadelphia stands at 56-45. ESPN Analytics gives the Dodgers a 68.9% chance of winning and the Phillies a 31.1% probability. At the time of this writing the odds were not released. Before making any wagers on Wednesday’s matchup, be sure to check out our free MLB picks.
Starting Pitchers Face Off at Citizens Bank Park
Eric Lauer is scheduled to start for Los Angeles and enters with a 4-5 record, a 4.81 ERA, and a 1.28 WHIP. The left-hander has pitched 76.2 innings, allowing 71 hits, 27 walks, and 18 home runs while recording 47 strikeouts. Aaron Nola gets the start for Philadelphia. The right-hander carries a 3-7 record with a 5.68 ERA and a 1.45 WHIP across 103 innings. He has surrendered 114 hits, 35 walks, and 23 home runs while collecting 108 strikeouts.
Los Angeles Seeks an Offensive Answer on the Road
Los Angeles enters Wednesday with a 63-38 overall record and a 32-19 mark away from home. The Dodgers are 2-3 over their last five games after recently losing to Philadelphia 10-7. They also recently lost to New York 2-1, defeated New York by scores of 8-2 and 2-1, and fell to Arizona 5-3. Three of their last five games were decided by exactly one run, while the other two produced margins of three runs or more.
The Dodgers are batting .260 with 885 hits, 524 runs, and 131 home runs. They have recorded a .342 on-base percentage and a .431 slugging percentage. The Los Angeles pitching staff carries a 3.56 ERA and a 1.14 WHIP while issuing 303 walks and recording 899 strikeouts. Opposing hitters are batting .217 against the Dodgers. Los Angeles has also produced a 15-10 record in day games.
Los Angeles owns the statistical advantage in nearly every supplied category. The Dodgers have the higher batting average, on-base percentage, and slugging percentage, along with 82 more hits and 82 more runs than Philadelphia. Their pitching staff holds a 0.68 advantage in ERA and a 0.18 edge in WHIP while limiting opponents to a batting average that is 38 points lower. Los Angeles also has the stronger overall and road records, but the Dodgers must respond after allowing 10 runs in the recent series meeting.
Philadelphia Looks to Capitalize on Its Power Advantage
Philadelphia enters the matchup with a 56-45 overall record and a 27-23 mark at Citizens Bank Park. The Phillies are 3-2 across their last five contests after recently defeating Los Angeles 10-7. Philadelphia also recently earned victories of 6-1 over New York and 5-0 over Detroit. Its two losses during this stretch were both against New York, coming by scores of 6-1 and 4-1. The Phillies scored at least five runs in each of their three victories but were held to one run in both defeats.
The Phillies are batting .237 with 803 hits, 442 runs, and 133 home runs. They own a .304 on-base percentage and a .403 slugging percentage. Philadelphia’s pitching staff has registered a 4.24 ERA and a 1.32 WHIP while issuing 297 walks and collecting 986 strikeouts. Opponents are batting .255 against the Phillies. Philadelphia has gone 17-19 in day games this season.
Philadelphia’s most notable offensive strength is its power production. The Phillies have hit 133 home runs, two more than Los Angeles, despite trailing the Dodgers in batting average, hits, runs, on-base percentage, and slugging percentage. Philadelphia’s pitching staff has also recorded 87 more strikeouts and issued six fewer walks. The concerns are its higher ERA, higher WHIP, and elevated opposing batting average. Philadelphia showed in the recent meeting that it can produce enough offense to challenge Los Angeles, but repeating that performance against the Dodgers’ stronger overall pitching staff will be difficult.
Los Angeles Dodgers vs Philadelphia Phillies Picks and Prediction
Los Angeles Dodgers vs Philadelphia Phillies Pick
- Pick: Los Angeles Dodgers Moneyline
I am backing Los Angeles to respond with a road victory. Philadelphia won the recent meeting 10-7, but the broader statistical comparison strongly favors the Dodgers. Los Angeles has the better overall record, stronger road mark, higher batting average, and substantially better team pitching numbers. The Dodgers also have the more favorable starting-pitcher comparison, with a 4.81 ERA and 1.28 WHIP against Philadelphia’s 5.68 ERA and 1.45 WHIP. ESPN Analytics gives Los Angeles a commanding 68.9% probability, and the Dodgers’ advantages on both sides make them the preferred selection.
Los Angeles Dodgers vs Philadelphia Phillies Total Pick
- Take the over if the total is set at 9.0.
I would take the over at 9.0. These teams recently combined for 17 runs in Philadelphia’s 10-7 victory, and both scheduled starters enter with ERAs above 4.80. The Philadelphia starter has surrendered 23 home runs in 103 innings, while the Los Angeles starter has allowed 18 in 76.2 innings. The teams have combined for 264 home runs this season, and each lineup has demonstrated the ability to produce a high-scoring performance recently. Those factors support another game reaching at least 10 combined runs.
Final Score Prediction: Los Angeles Dodgers 7 – Philadelphia Phillies 4
This prediction was written before the completion of game play on Tuesday.