Los Angeles Dodgers vs San Francisco Giants Picks and Prediction for Sunday September 27 2026

By: Kim Smith Published 09/27/2026, 12:30 AM ET

The Los Angeles Dodgers visit the San Francisco Giants at Oracle Park in San Francisco, California, on Sunday, September 27, 2026. First pitch is scheduled for 3:05 PM ET with coverage on MLB.TV. Los Angeles enters at 98-62 overall and 47-32 on the road, while San Francisco is 65-95 overall and 37-42 at home. The Dodgers lead the NL West by nine games over San Diego, while the Giants sit fourth, 33 games behind Los Angeles. The Dodgers won Friday's series opener 2-0, while Saturday's game had not been completed when this preview was prepared and is excluded from the analysis. Los Angeles has also won the last two completed meetings between these clubs while holding San Francisco to one total run. At the time of this writing the odds were not released. Be sure to check out our free MLB picks for more MLB predictions throughout the season.

Starting Pitchers

Neither Los Angeles nor San Francisco had a probable starting pitcher listed for Sunday's game in the supplied information when this preview was completed. That creates some uncertainty for both the side and total, especially with the regular season reaching its final weekend and pitching plans potentially changing. Bettors should confirm the starting matchup before placing a wager. Based on the information currently available, the handicap has to rely more heavily on each team's full-season pitching performance, recent run prevention and offensive production.

Dodgers Continue to Control the NL West

Los Angeles enters Sunday at 98-62 overall and has gone 3-2 across its last five completed games. The Dodgers opened this series with a 2-0 victory Friday after losing consecutive games against San Diego by scores of 4-2 and 5-1. Los Angeles previously shut out the Padres 7-0 and defeated San Francisco 3-1 on September 20. The Dodgers have therefore allowed only ten runs across those five contests, including two shutouts.

Los Angeles is batting .257 with 792 runs, 1,382 hits and 201 home runs. The Dodgers own a .338 on-base percentage and .425 slugging percentage, giving them clear advantages over San Francisco in every major offensive category supplied. The pitching staff has been even more impressive, recording a 3.57 ERA and 1.14 WHIP with 1,495 strikeouts against only 477 walks. Opponents are hitting just .218 against Los Angeles.

That combination of offense and pitching makes the Dodgers extremely difficult to attack. Los Angeles has scored 127 more runs than San Francisco while allowing opponents to hit 30 points lower. The Dodgers also hold a substantial strikeout advantage, and their 1.14 WHIP suggests they consistently limit the number of baserunners available to opposing offenses. Even without knowing Sunday's starter, the overall pitching environment strongly favors Los Angeles.

Giants Struggling to Generate Consistent Offense

San Francisco enters Sunday at 65-95 overall and has lost four of its last five completed games, including three straight. The Giants were shut out 2-0 by Los Angeles on Friday after losing consecutive games to Minnesota by scores of 4-2 and 3-2. Their lone victory during the five-game stretch was a 5-2 win over Minnesota, while the other defeat came 3-1 against the Dodgers. San Francisco has scored only ten runs across its last five games.

The Giants are batting .245 with 665 runs, 1,327 hits and 178 home runs. They have produced a .307 on-base percentage and .401 slugging percentage. On the mound, San Francisco owns a 4.34 ERA and 1.36 WHIP with 1,187 strikeouts against 587 walks while allowing opponents to bat .248.

The biggest concern is San Francisco's ability to generate enough offense against Los Angeles pitching. The Giants have managed only one run in their last two completed games against the Dodgers and have failed to exceed two runs in four of their last five overall. San Francisco's .307 OBP also creates a difficult matchup against a Dodgers staff allowing only a .218 opponent batting average. Unless the Giants can dramatically improve their ability to reach base, their margin for error remains extremely small.

Los Angeles Dodgers vs San Francisco Giants Picks and Prediction

Pick: Los Angeles Dodgers Moneyline

Los Angeles is the preferred side based on advantages in virtually every meaningful season-long category. The Dodgers have the better batting average, OBP and slugging percentage while scoring 127 more runs and hitting 23 more home runs. The difference becomes even more pronounced on the mound, where Los Angeles owns a 3.57 ERA and 1.14 WHIP compared with San Francisco's 4.34 ERA and 1.36 WHIP. Dodgers pitching has also limited opponents to a .218 average, while the Giants have struggled to score recently. Los Angeles has won the last two completed meetings while allowing only one combined run. The eventual starting-pitcher announcements matter, but the overall matchup still points toward the Dodgers.

Pick: Under 8.0 or Higher

The under is the preferred total at 8.0 or higher. Los Angeles has allowed only ten runs over its last five completed games, while San Francisco has scored only ten during the same span. Four of the Giants' last five games have finished with six or fewer combined runs, and each of the last two completed Dodgers-Giants meetings stayed comfortably below eight with final scores of 3-1 and 2-0. The Dodgers' 3.57 team ERA, 1.14 WHIP and .218 opponent batting average provide additional support for another difficult afternoon for the San Francisco offense. With neither starter confirmed, the number should still be checked before wagering, but eight or better provides enough room to back another low-scoring matchup.

Final Picks: Los Angeles Dodgers Moneyline and Under 8.0 or Higher

This preview was completed on Saturday, September 26, 2026. Starting pitchers, betting lines and other game information are subject to change before the game begins.

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