Milwaukee Brewers vs. Chicago Cubs Picks and Prediction for Wednesday, October 8, 2025
In our Brewers vs. Cubs prediction, the Milwaukee Brewers are looking to sweep the NLDS and get some rest as they are up with a 2-0 series lead. Young right-hander Quinn Priester will be taking the mound for the first time this postseason as he has not pitched in a game since Sept. 26 against the Cincinnati Reds, where he pitched five innings and allowed three runs on nine hits with one walk and four strikeouts in a losing effort.
The Chicago Cubs have their backs against the wall as they are down 0-2 in a best-of-five NLDS as they head home. Veteran right-hander Jameson Taillon gets the start and pitched in Game 3 of the NL Wild Card, where he did not factor into the decision as he threw four shutout innings and gave up two hits with zero walks and four strikeouts.
Dial in your read with MLB picks for Milwaukee Brewers vs. Chicago Cubs before first pitch.
Brewers Looking for the Brooms
The Milwaukee Brewers have been on fire offensively as they are second in MLB during the postseason with a .939 team OPS while scoring 8.0 runs per game. The team has been getting hits at an incredible rate as their .343 team batting average only trails the Toronto Blue Jays in these playoffs. Left fielder Jackson Chourio has swung the bat well to begin the postseason as he is 5-for-7 with one home run, six RBI, and two runs scored thus far.
Quinn Priester is in the 68th percentile in xERA, 66th percentile in barrel percentage, 59th percentile in hard hit percentage, and 57th percentile in average exit velocity according to his Baseball Savant page. He has five different pitches (sinker, slider, cutter, curveball, changeup) and his curveball has been his best pitch as hitters have a .143 batting average and .347 slugging percentage with three home runs and 20 strikeouts. Priester faced the Cubs three times during the regular season and was 1-0 in 14.1 innings and gave up 10 runs on 17 hits with one hit by pitch, 11 walks, and 11 strikeouts.
Injury Report for Milwaukee
- Pitcher Brandon Woodruff: Lat (OUT)
- Pitcher Jose Quintana: Calf (OUT)
- Pitcher Shelby Miller: Elbow (OUT)
- Pitcher Logan Henderson: Elbow (OUT)
- Pitcher Jordan Montgomery: Elbow (OUT)
- Center fielder Garrett Mitchell: Oblique (OUT)
- Pitcher Connor Thomas: Elbow (OUT)
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Cubs Looking to Keep Their Season Alive
The Chicago Cubs have been holding their own offensively in the playoffs as they are sixth in the sport with a .657 team OPS while averaging 2.4 runs per game. The team has been able to hit for power as they are second in the majors this playoffs with seven home runs. First baseman Michael Busch had a good start to the playoffs as he has gone 5-for-16 with two home runs, two RBI, two runs scored, and a 1:1 walk-to-strikeout ratio in five games.
Jameson Taillon’s Baseball Savant page has him in the 16th percentile in whiff percentage, 22nd percentile in strikeout percentage, 46th percentile in xBA, and 53rd percentile in barrel percentage. He has a six-pitch arsenal (fastball, sweeper, cutter, curveball, changeup, sinker) and his curveball has been his best pitch as hitters have a .148 batting average and .148 slugging percentage with zero extra-base hits and 15 strikeouts against it. Taillon faced the Brewers three times during the regular season as he went 2-1 in 16.0 innings and allowed eight runs on 16 hits with three walks and 11 strikeouts.
Injury Report for Chicago
- Pitcher Cade Horton: Ribs (OUT)
- Right fielder Owen Caissie: Concussion (OUT)
- Pitcher Ryan Braiser: Groin (OUT)
- Catcher Miguel Amaya: Ankle (OUT)
- Pitcher Justin Steele: Elbow (OUT)
Milwaukee Brewers vs. Chicago Cubs Pick
Spread Pick for Brewers vs. Cubs
- Chicago Cubs -137 (4 units)
This series has been too back-and-forth to feel like a sweep is happening. The Cubs are sending an experienced Jameson Taillon to the mound and have a team that has a lot of playoff experience with names like Kyle Tucker and Dansby Swanson, so they are going to be able to step up and play well. Quinn Priester is pitching in his first career postseason game and is on the road, so seeing how he pitches against a hostile Chicago crowd could be interesting for a pitcher who hasn’t pitched in almost two weeks.
Over/Under Pick for Brewers vs. Cubs
- UNDER (4 units)
These bullpens have been incredible throughout the postseason as Milwaukee is best in the majors with a 0.84 reliever ERA, while Chicago is fourth with a 2.67 bullpen ERA up to this point. Quinn Priester is coming into this game with extended rest, while Jameson Taillon is an experienced pitcher who has pitched in difficult situations like an elimination game. Manager Craig Counsell knows how to manage situations like this so expect the runs to be limited at Wrigley Field and the UNDER to hit.
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