Milwaukee Brewers vs Cincinnati Reds Picks and Prediction for Monday June 22 2026

The Milwaukee Brewers and Cincinnati Reds meet at Great American Ball Park in Cincinnati, Ohio on Monday, June 22, 2026, with first pitch scheduled for 7:10 PM ET. The game will be televised on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers Ready for Division Battle

Milwaukee is expected to start Brandon Woodruff in this matchup. Woodruff enters with a 2-1 record, a 3.60 ERA, and a 1.03 WHIP across 30.0 innings. He has allowed 24 hits while striking out 25 batters, issuing 7 walks, and surrendering 4 home runs.

Cincinnati is expected to counter with Brady Singer. Singer comes into the game with a 3-6 record, a 5.32 ERA, and a 1.61 WHIP over 66.0 innings. He has allowed 83 hits while recording 52 strikeouts, issuing 23 walks, and giving up 17 home runs.

Milwaukee Aims to Stay Near the Top

The Brewers enter Monday's contest with a 45-29 overall record and a strong 20-14 record on the road. Milwaukee has won two of its last five games, recently defeating Cleveland twice before dropping three consecutive games against Cleveland and Atlanta. Despite the recent skid, the Brewers still carry one of the best records among the teams in action on Monday.

Milwaukee owns a .255 team batting average with 388 runs scored, 640 hits, and 67 home runs. The Brewers have produced a .339 on-base percentage and a .393 slugging percentage. Their pitching staff has been outstanding, posting a 3.44 ERA and a 1.20 WHIP while holding opponents to a .223 batting average. Milwaukee pitchers have recorded 727 strikeouts and issued 247 walks.

The biggest strength for Milwaukee is its complete balance. The Brewers have the better batting average, on-base percentage, ERA, WHIP, strikeout total, and opponent batting average in this matchup. Their pitching staff has consistently limited opposing offenses while the lineup has generated enough offense to support one of the strongest records in the league.

Cincinnati Returns Home Looking for Momentum

The Reds come into this game with a 36-39 overall record and a 19-19 record at home. Cincinnati has won three of its last five games, recently defeating New York Yankees and New York Mets twice. The Reds also suffered losses to New York Mets and another game against New York Yankees during that stretch, but they enter this series after an impressive 10-2 victory in their most recent contest.

Cincinnati has posted a .229 batting average with 321 runs scored, 577 hits, and 95 home runs this season. The Reds own a .312 on-base percentage and a .395 slugging percentage. On the mound, Cincinnati carries a 4.63 ERA and a 1.47 WHIP while allowing opponents to hit .251. Reds pitchers have recorded 587 strikeouts and issued 341 walks.

One area where Cincinnati stands out is power production. The Reds have hit 95 home runs, far more than Milwaukee's 67. However, that advantage has been offset by lower batting averages, fewer hits, fewer runs scored, and significantly weaker pitching numbers throughout the season.

Milwaukee Brewers vs Cincinnati Reds Picks and Prediction

Milwaukee Brewers vs Cincinnati Reds Pick

• Pick: Milwaukee Brewers Moneyline

Milwaukee enters this matchup with a substantial advantage in ESPN's matchup predictor and owns the better overall record, road record, and team statistics. The Brewers lead the Reds in batting average, runs scored, hits, on-base percentage, ERA, WHIP, strikeouts, and opponent batting average. Combined with the stronger numbers from their expected starting pitcher, Milwaukee appears to have the edge in this divisional matchup.

Milwaukee Brewers vs Cincinnati Reds Total Pick

• Pick: Take the over if the total is set at 8.5

I would lean toward the over if the total is set at 8.5. Cincinnati has hit 95 home runs this season while Milwaukee has scored 388 runs and collected 640 hits. The Reds' pitching staff has allowed a .251 opponent batting average and carries a 4.63 ERA, which could create opportunities for Milwaukee's offense. Those factors make the over appealing at this number.

Final Score Prediction: Milwaukee Brewers 6 – Cincinnati Reds 4

This prediction was written before the completion of game play on Sunday.