Milwaukee Brewers vs Pittsbugrh Pirates Picks and Prediction, Friday, September 5, 2025
The Milwaukee Brewers are on the road to play the Pittsburgh Pirates on Friday, September 5 at 6:40 p.m. ET, so continue reading for our Brewers vs Pirates prediction. This is written before Thursday's game has ended.
When it comes to baseball picks, our MLB Predictions are stellar.
Brewers Have Best Record in Baseball
Milwaukee enters play on Thursday with a record of 86-54, which is the best record in the MLB. The Brewers have split the first two games against the Phillies before the series finale on Thursday, before continuing their road trip against the Pirates. Milwaukee is hitting .259, which ranks second, while on the road is hitting .273. Against the Pirates this season, Milwaukee is hitting .297 in 10 games.
The Brewers will be starting right-hander Quinn Priester, who's 11-2 with a 3.28 ERA in 25 games, including 20 starts this season. Last time out, Priester went 6 scoreless innings against the Blue Jays. In his career against the Pirates, he went 6 innings, allowing 1 run earlier this season. Milwaukee has a team ERA of 3.65, which ranks second.
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Pirates Last in NL Central
Pittsburgh enters play on Thursday with a record of 63-77, which is last in the NL Central. The Pirates have won the first two games against the Dodgers at home and are looking for the sweep on Thursday. Pittsburgh is expected to start right-hander Johan Oviedo, who's 2-0 with a 3.60 ERA in 4 starts this season. Last time out, he went 5 innings, allowing 2 runs against the Red Sox. Pittsburgh has a team ERA of 3.91, which ranks 15th.
The Pirates are hitting .234, which ranks 28th, while at home are hitting .252. Against Priester, McCutchen, Cruz, Horwitz, and Reynolds are all 1-for-3, Canario is 2-for-6 with a homer, and Davis and Pham are 0-for-1.
Brewers -1.5 (5 Units)
Milwaukee is the best team in the majors, and with Priester on the mound, this is a great spot for the Brewers on the run line. Priester has been dominant this season, and he should be able to limit the Pirates' offense, which is one of the worst in the majors. Meanwhile, Milwaukee's offense is potent and should be able to take advantage of Oviedo and the bullpen to cruise to a lopsided win here. The Brewers are 78-62 on the run line this season, so look for those trends to continue here.
Take the Brewers -1.5.
Under (4 Units)
The under is also a great spot here as Priester and Oviedo have pitched well this season, and both will limit the runs. Meanwhile, the Pirates' offense has struggled and will struggle to produce many hits or runs, as this seems like a 4-1 type of win for the Brewers here. This season, Milwaukee is 68-66-6 in hitting the under while the Pirates are 77-58-5 which is the second-best under record in the majors.
Take the under.
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