Milwaukee Brewers vs San Diego Padres Picks and Prediction for Wednesday August 12 2026

The Milwaukee Brewers will face the San Diego Padres on Wednesday afternoon at Petco Park in San Diego, California. First pitch is scheduled for 4:10 PM ET, with MLB.TV providing coverage. Milwaukee enters the matchup at 74-45 overall and 33-23 on the road, while San Diego is 63-57 overall and 35-26 at home. At the time of this writing the odds were not released. Bettors looking for more baseball analysis can also check out free MLB picks.

Starting Pitchers

Milwaukee is expected to start Dustin May, who enters at 6-7 with a 4.30 ERA and 1.27 WHIP across 115 innings. May has allowed 108 hits while striking out 111 and walking 38, with only eight home runs surrendered. San Diego is expected to counter with Robbie Ray, who comes in at 10-7 with a 3.24 ERA and 1.33 WHIP through 127.2 innings. Ray has allowed 108 hits, 62 walks and 16 home runs while recording 109 strikeouts.

Brewers Continue to Lead the NL Central

Milwaukee enters Wednesday with the best record in the NL Central at 74-45 and has been strong away from home at 33-23. The Brewers have won three of their last five games, although they dropped Monday's series opener in San Diego by a 3-2 score. Their recent victories include consecutive 4-3 wins over Minnesota and a 5-2 win over Pittsburgh.

The Brewers are batting .252 this season with 587 runs, 1,012 hits and 110 home runs. Milwaukee owns a .336 on-base percentage and .398 slugging percentage. Jackson Chourio leads the club with a .280 batting average, while Brice Turang has driven in a team-high 74 runs and Jake Bauers leads the Brewers with 21 home runs.

Milwaukee's pitching staff is one of the major reasons for its strong record. The Brewers own a 3.47 team ERA and 1.16 WHIP while holding opponents to a .219 batting average. May's 4.30 ERA is higher than the team mark, but his ability to limit home runs gives Milwaukee a chance to keep this game under control.

Padres Riding a Strong Recent Stretch

San Diego enters the matchup at 63-57 overall and has played well at Petco Park with a 35-26 home record. The Padres have won four of their last five games, including Monday's 3-2 victory over Milwaukee. San Diego also took two of three from Houston and picked up a 5-1 road win against Arizona.

The Padres are batting .236 with 507 runs, 932 hits and 130 home runs while posting a .312 on-base percentage and .386 slugging percentage. Fernando Tatis Jr. leads the team with a .280 batting average, while Manny Machado has supplied 23 home runs and a team-high 70 RBI.

San Diego has a 4.14 team ERA and 1.32 WHIP, but Ray gives the Padres a stronger-than-average starting option. His 3.24 ERA is better than May's 4.30 mark, though the 62 walks in 127.2 innings could create opportunities for a Brewers lineup that owns a strong .336 OBP.

Milwaukee Brewers vs San Diego Padres Picks and Prediction

Pick: Milwaukee Brewers Moneyline

San Diego has the better starting-pitcher ERA and has been playing well recently, but Milwaukee still has the stronger overall profile. The Brewers own the better record, have been successful on the road and hold clear advantages in team ERA, WHIP and on-base percentage. Ray's walk total also gives Milwaukee a path to create scoring chances even if hits are difficult to come by. Take Milwaukee on the moneyline.

Pick: Under 8.0

This matchup has the look of another lower-scoring game. San Diego won the series opener 3-2, Milwaukee owns a 3.47 team ERA, and Ray brings a 3.24 ERA into Wednesday. May has also been effective at keeping the ball in the park, allowing only eight home runs over 115 innings. With both clubs backed by capable pitching, take the under if the total is set at 8.0.

This game was completed prior to play on Tuesday.