Milwaukee Brewers vs Tampa Bay Rays Picks and Prediction for Wednesday October 28 2026

Game Five of the World Series will take place on Wednesday night, when the Milwaukee Brewers battle the Tampa Bay Rays. First pitch is scheduled for October 28, 2026 at 8:00 pm EST. Tropicana Field will be the scene and the game will be televised on Fox. Odds makers have installed the Brewers as a -130 road favorite and the total is sitting at 6.5. Be sure to check out our free MLB picks for more MLB predictions throughout the postseason.

Milwaukee turns to their ace

The Milwaukee Brewers have won ten of their first 12 playoff games and are one win away from the first World Series title. The Brewers (3-1) accomplished the improbable by sweeping the Los Angeles Dodgers in the NLCS and are 4-2 on the road this postseason. In Game Four, Milwaukee rookie SS Cooper Pratt went 4-for-5 with a home run and two RBIs during a 4-3 road loss in 12 innings. 

Twenty-four year old righty Jacob Misiorowski (16-5 1.80 ERA) will take the ball for the Brewers. For the season, Misiorowski ranked first in the majors in ERA, strikeouts (252), and WHIP (0.80). In Game One, Misiorowski allowed one run in five innings during a 3-2 home victory. Milwaukee closer Trevor Megill has notched five saves this postseason and was only used to record one out last night. 

Milwaukee leads all playoff teams with a .766 OPS and has hit 12 home runs in 12 games. Pratt’s solo shot in the 12th inning was nearly a series clinching blast. Leadoff hitter Jackson Chourio went 2-for-6 last night and has contributed a team-high nine postseason RBIs for the Brewers.

Tampa Bay trying to stave off elimination

The Tampa Bay Rays have won five of their first seven home playoff games and are one victory away from getting this series back to Milwaukee. The Rays (1-3) are looking to become the first team in MLB history to rally from a 3-0 series deficit to win a World Series. During Tuesday’s home victory, Jonny DeLuca tied the game in the 12th inning with an RBI single. Pinch-hitter Ben Williamson walked it off for the Rays on a single that scored Nick Fortes with the winning run. 

Tampa Bay manager Kevin Cash has yet to name a starting pitcher for Game Five. Nick Martinez started the series opener for the Rays, but was used for two scoreless innings last night. The Rays ranked 15th in the majors with a 4.12 bullpen ERA and closer Bryan Baker (9 IP) has notched five saves while not allowing a run in the playoffs. 

For the playoffs, Tampa Bay ranks sixth with a .614 OPS and have hit eight long balls. The Rays averaged 4.54 runs scored during the regular season, but have seen that dip a full run in the playoffs. Leadoff hitter Yandy Diaz leads Tampa Bay with 14 hits and eight runs. OF Chandler Simpson is hitting .293 with five stolen bases for the Rays.

Milwaukee Brewers vs Tampa Bay Rays Picks and Prediction

Pick: Milwaukee Brewers -130

Tampa Bay 3B Junior Caminero exited Game Four with a potential right leg injury and is listed as day-to-day. Milwaukee was three outs away from a World Series title, but a Joey Ortiz throwing error opened the door in the 12th inning. Tampa Bay followed with four singles and a victory. The Brewers have been swinging hotter bats and will respond at the plate. Take Milwaukee to win Game Five.

Pick: Over 6.5 (-110)

Milwaukee SP Jacob Misiorowski has not recorded more than 16 outs in the playoffs and Tampa Bay is a tough lineup to strike out. The Brewers will jump out to an early lead and the feast on an overused Rays’ bullpen. Tampa Bay has continued to battle and is good for a couple of runs once Misiorowski exits. Take the over.

Final Score Prediction: Milwaukee Brewers win 7-3