Minnesota Twins vs. Philadelphia Phillies Picks and Prediction for Sunday, September 28, 2025

By: Justin Walker Published 09/28/2025, 12:23 AM ET
Minnesota Twins vs. Philadelphia Phillies Picks and Prediction
Use Code SSWC

In the final game of the 2025 regular season, the Minnesota Twins are taking on the Philadelphia Phillies inside Citizens Bank Park on Sunday afternoon in our Twins vs. Phillies prediction. The Twins were able to record a 5-0 road win on Saturday. The Twins are fourth in the AL Central with a 70-91 record and are sending young right-hander Simeon Woods Richardson to the mound. The Phillies are first in the NL East with a 79-74 record and have righty Cristopher Sanchez getting the ball. Todayโ€™s edge: MLB predictions for Minnesota Twins vs. Philadelphia Phillies built on form and matchups.

Twins Looking to End Year with a Win

The Minnesota Twinsย are looking to end the year strong after their 5-0 road win over the Philadelphia Phillies on Saturday. The lineup was able to go 11-for-36 with two walks and 11 strikeouts on the day as Byron Buxton, Jake Outman, and Ryan Fitzgerald all homered. The Twins went 0-for-5 with runners in scoring position and stranded six men on base. Mick Abel looked sharp with six shutout innings to record the win.

ย 

The Twins are sending young right-hander Simeon Woods Richardson to pitch and he is holding his own. In 22 games (21 starts), he is 7-4 in 105.1 innings with a 4.27 ERA and a 1.34 WHIP. He has been able to limit hits, as he allowed a .238 batting average against. Richardson faced the Phillies once last season in a no-decision as he pitched six shutout innings, giving up three hits with one walk and five strikeouts.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that StatSalt may use third-party services to process my data.

ย 

Injury Report for Minnesota

  • Second baseman Luke Keaschall: Thumb (OUT)
  • Pitcher Pablo Lopez: Forearm (OUT)
  • Right fielder Matt Wallner: Oblique (OUT)
  • Pitcher Justin Topa: Oblique (OUT)
  • Left fielder Alan Roden: Thumb (OUT)
  • Pitcher Anthony Misiewicz: Shoulder (OUT)
  • Pitcher David Festa: Shoulder (OUT)

Phillies Fighting to Hold Wild Card Spot

The Philadelphia Phillies are gearing up for the playoffs after Saturdayโ€™s 5-0 home loss against the Minnesota Twins in their most recent game. They won the NL East by double digits, so they can sit back and wait for the wild card winner. The Phillies were able to go 7-for-33 with one walk and 13 strikeouts at the plate as a team. Philly finished 0-for-3 with runners in scoring position while leaving seven men on base. Ranger Suarez struggled in the loss as he allowed three runs in 4.1 innings.

ย 

Right-hander Cristopher Sanchez is going to be taking the mound for the Philadelphia Phillies in this game and has been doing well as he is 13-5 with a 2.57 ERA and a 1.08 WHIP in 196.1 innings over 31 starts. He has been doing an amazing job in limiting homers, as he has given up 12 so far. Sanchez faced the Phillies once in 2023 in a win as he allowed two runs on six hits with three walks and five strikeouts in six innings of work.

ย 

Injury Report for Philadelphia

  • Left fielder Max Kepler: Illness (Questionable)
  • Pitcher Jose Alvarado: Forearm (OUT)
  • Shortstop Trea Turner: Hamstring (OUT)
  • Pitcher Daniel Robert: Forearm (OUT)
  • Pitcher Zack Wheeler: Blood Clot (OUT)
  • Pitcher Jordan Romano: Finger (OUT)

Minnesota Twins vs. Philadelphia Phillies Pick

Spread Pick for Twins vs. Phillies

  • Philadelphia Phillies ML (5 units)

With the Phillies getting a bye in the NL Wild Card, they are not going to play again until next weekend so they are going to be getting their pitchers ready for the rest. The Twins are 20th in MLB with a .697 road OPS as a team, while the Phillies are best in the sport with a .817 home OPS heading into the season finale. Phillyโ€™s bullpen is shaping up as well so go with them to end the regular season with a home win.

Over/Under Pick for Twins vs. Phillies

  • Under (4 units)

In September, these starting pitchers are stepping up as Simeon Woods Richardson is 2-0 with a 3.00 ERA and a .162 batting average against in 21.0 innings (four starts) while Cristopher Sanchez is 2-0 with a 2.00 ERA and a 0.85 WHIP in 27.0 innings (four starts) so far. Both teams are limiting the amount of homers hit against them as Minnesota is 18th with 193 home runs hit while Philadelphia is 13th with 177 allowed. The under is 5-4-1 in their previous 10 games against each other, so take the under here.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Review
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users โ€“ Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Review
Requirement New Users โ€“ Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
Fanatics

10 x $100 bet match in FanCash

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Fanatics Review
Cashable No
>

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright ยฉ 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.