New York Yankees vs. Baltimore Orioles Picks and Prediction, Thursday, September 18, 2025
In the opener of a late-season AL East series, the Orioles (72-80) look to throw a wrench into the Yankees' (85-67) playoff hopes. Baltimore has been eliminated from the playoffs, and New York is in the top spot in the Wild Card. These teams face off in seven of the last 10 regular-season games. Here in this New York Yankees vs. Baltimore Orioles prediction, you can check out the full score info, pitching matchup, and other free MLB picks.
The Yankees are a big road favorite in this game, posted at -190 with the Orioles at +160 and a total of 9 runs.
Grisham Does it Again for the Yankees
After losing two in a row, the Yankees have won their last two games, where they scored 10 runs in each. In their last game, they were on the road in a 10-5 win over the Minnesota Twins, where Trent Grisham went yard twice with four RBI, and Cody Bellinger had a HR and three RBI. The Bronx Bombers are 6-4 in their last 10 games and are in second place in the AL East, four games back of the Toronto Blue Jays.
- On the season, New York is the highest-scoring team in the Majors but only ranks 18th in team ERA.
- MVP candidate Aaron Judge (.329 48 HR 103 RBI) leads baseball in batting average, ranks fourth in HR, and has two HR and three RBI in the last six games.
- Bellinger (.275 29 HR 97 RBI) leads the club in at-bats and has six RBI in the last six games.
- On the season, the Yankees are 41-36 on the road.
Max Fried (17-5 3.03 ERA, 1.13 WHIP) takes the hill for Game 1 and in his last start, gave up two runs on nine hits in 5 1/3 innings in a 5-3 win over the Boston Red Sox. The Yankees have won his last four starts and have given up a total of five runs in his last two outings while only giving up one in the two before that. In Fried’s lone start against the Orioles this season he gave up three runs in six innings in a loss.
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Orioles on the Right Side of the Broom In Their Last Series
After getting swept in a three-game set by the Toronto Blue Jays, the Orioles got the sweep in their last series, winning three in a row over the Chicago White Sox. In their last game, they were on the road in a 3-1 win over the Chicago White Sox, where Dylan Beavers had a two-run HR and Jeremiah Jackson had an RBI. While Baltimore is 6-4 in their last 10 games, they are still in the basement of the AL East and have officially been eliminated from the playoffs.
- On the season, the Orioles rank tied for 21st in the Majors in runs scored and 24th in team ERA.
- Gunnar Henderson (.274 16 HR 64 RBI) leads the team in batting average and RBI and has three RBI over the last five games.
- Jackson Holliday (.250 17 HR 55 RBI) is the club leader in HR, and while batting .327 this month, he has not gone yard in the last nine games.
- On the season, the Orioles are 36-38 at home.
Cade Povich (3-7 5.05 ERA 1.45 WHIP) gets the nod in the series opener and, in his last start gave up two runs on five hits in 5 2/3 innings in a 3-2 win over the Pittsburgh Pirates. The Orioles have won his last two starts, where he gave up a total of six runs in 10 2/3 innings, after losing his previous five outings. In Povich’s lone start against the Yankees this season, he gave up three runs in 4 2/3 innings in a win.
New York Yankees vs. Baltimore Orioles Pick
Yankees vs. Orioles
- Yankees - run line -1.5 runs -120
Both the Yankees and Orioles are 6-4 in their last 10 games, and they have split the six games facing each other this season. Fried is tied for the lead in the bigs in wins, has been pitching pretty well as of late, and will have a good outing in this game ,facing a Baltimore lineup that only ranks tied for 21st in runs scored. Povich has been up and down recently, but he and the Baltimore bullpen, which only ranks 25th in bullpen ERA, will be roughed up by the Yankees’ lineup, which has scored the most runs this season and has totaled 10 runs in each of the last two games. Regarding the New York Yankees vs. Baltimore prediction, the Yankees will be better at the dish and on the hill and will take the opener of this division series. New York will also win by at least two runs, so take the run line to get better odds.
Over/Under Pick for New York Yankees vs. Baltimore Orioles
- Over 9 runs
The Bronx Bombers have lived up to their moniker this season, as the highest-scoring team in the Majors. They have scored 10 runs in each of their last two games and will have another big game at the dish in this game. They will do so facing Povich, who has an ERA north of 5.00 and an Orioles’ bullpen that only ranks 25th in bullpen ERA. Fried has been pitching well as of late and will have another good outing in this series opener. The Orioles will score some runs, but not many, while the opposite will be true for the Yankees, which is why the pick for this Game 1 is the Over.
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