San Francisco Giants vs Arizona Diamondbacks Picks and Prediction for Wednesday July 1 2026

The San Francisco Giants travel to Chase Field to face the Arizona Diamondbacks on Wednesday, July 1, 2026. First pitch is scheduled for 9:40 PM ET, with coverage on MLB.TV. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers for San Francisco Giants vs Arizona Diamondbacks

Trevor McDonald is scheduled to start for San Francisco. He enters the game with a 2-6 record, a 4.94 ERA, a 1.35 WHIP, and 51.0 innings pitched. He has allowed 50 hits, struck out 45 batters, walked 19, and surrendered four home runs. Zac Gallen is expected to start for Arizona with a 3-7 record, a 6.15 ERA, a 1.58 WHIP, and 86.1 innings pitched. He has allowed 109 hits, struck out 52 batters, walked 27, and given up 15 home runs.

San Francisco Looks to End Its Road Struggles

The Giants enter this matchup with a 35-49 overall record and a 17-27 road record. San Francisco recently lost to Arizona 5-4 after winning back-to-back games over Atlanta by scores of 3-2 and 5-0. Before those victories, the Giants dropped a 3-1 decision to Atlanta and a 9-6 game to the Athletics. San Francisco has posted a 2-3 record over its last five games.

The Giants have compiled a .256 batting average with 341 runs, 736 hits, and 89 home runs. They own a .308 on-base percentage and a .417 slugging percentage. On the mound, San Francisco has recorded a 4.32 ERA with a 1.36 WHIP, issued 318 walks, struck out 650 batters, and held opponents to a .247 batting average. The Giants are 19-32 in night games.

The biggest strength for San Francisco is its ability to consistently put the ball in play. The Giants hold the advantage in batting average, hits, home runs, and slugging percentage over Arizona. If the offense continues to produce at those levels, San Francisco has an opportunity to stay competitive despite its road record.

Arizona Tries to Build on Its Latest Victory

The Diamondbacks come into Wednesday’s contest with a 42-42 overall record and a strong 25-17 home record. Arizona recently defeated San Francisco 5-4 after losing three straight games to Tampa Bay by scores of 5-1, 4-2, and 6-1. Before that skid, the Diamondbacks earned a 9-4 victory over St. Louis. They have gone 2-3 over their last five games.

Arizona enters the matchup batting .238 with 355 runs, 661 hits, and 76 home runs. The Diamondbacks have produced a .308 on-base percentage and a .386 slugging percentage. Their pitching staff owns a 4.33 ERA with a 1.30 WHIP, has issued 249 walks, recorded 571 strikeouts, and allowed opponents to bat .252. Arizona is 25-25 in night games.

Arizona’s biggest advantage comes on the pitching side. The Diamondbacks own the lower WHIP, have issued fewer walks, and have held opponents to fewer baserunners overall than San Francisco. Combined with their winning home record, those numbers provide a solid foundation entering this game.

San Francisco Giants vs Arizona Diamondbacks Picks and Prediction

San Francisco Giants vs Arizona Diamondbacks Pick

• Pick: Arizona Diamondbacks Moneyline

I’ll take Arizona in this matchup. The Diamondbacks have the better overall record, a strong 25-17 home record, and they picked up a 5-4 victory over San Francisco in the most recent meeting. While the Giants hold the edge in several offensive categories, Arizona has been better at limiting baserunners with a lower team WHIP and fewer walks allowed. Playing at home gives the Diamondbacks the slight advantage.

San Francisco Giants vs Arizona Diamondbacks Total Pick

• Take the over if the total is set at 8.5.

I would lean toward the over if the total is set at 8.5. Both scheduled starters enter with ERAs above 4.90, including a 6.15 ERA for Arizona’s starter. The Giants have also hit 89 home runs this season, while Arizona has scored 355 runs. The previous meeting finished with nine total runs, and I see enough offense in the provided numbers for this game to finish above 8.5.

Final Score Prediction: Arizona Diamondbacks 6 – San Francisco Giants 5

This prediction was written before the completion of game play on Tuesday.