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San Francisco Giants vs Milwaukee Brewers Picks and Prediction for Wednesday June 3 2026

By: Kim Smith Published 06/03/2026, 05:55 AM ET
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The San Francisco Giants and Milwaukee Brewers continue their series on Wednesday, June 3, 2026, at American Family Field in Milwaukee, Wisconsin. First pitch is scheduled for 7:40 PM ET with coverage available on MLB.TV. At the time of this writing the odds were not released. San Francisco enters the matchup with a 23-37 record, while Milwaukee comes in at 36-21. The Brewers have been one of the strongest teams in the National League this season, while the Giants are trying to recover from a difficult loss in the series opener. Be sure to check out our free MLB picks.

Starting Pitchers for Wednesday's Matchup

San Francisco is expected to start Logan Webb in this contest. Webb enters the game with a 2-4 record, a 4.82 ERA, and a 1.39 WHIP across 52.1 innings. He has allowed 55 hits while striking out 47 batters, walking 18, and surrendering four home runs. Milwaukee has not yet announced a starting pitcher for Wednesday's game.

San Francisco Looking for a Better Performance

The Giants enter Wednesday's contest with a 23-37 overall record and an 11-21 mark on the road. San Francisco has lost four of its last five games. The Giants most recently suffered a 16-2 defeat against Milwaukee after previously losing two of three games against Colorado and another contest against Arizona. Their lone victory during the last five games came in a 19-6 win over Colorado.

San Francisco is batting .252 as a team while scoring 234 runs on 520 hits. The Giants have hit 54 home runs and own a .300 on-base percentage with a .403 slugging percentage. On the mound, San Francisco has posted a 4.54 ERA and a 1.40 WHIP while allowing opponents to hit .252. The pitching staff has recorded 474 strikeouts and issued 236 walks.

The biggest strength for San Francisco has been its ability to collect hits. The Giants have accumulated 520 hits this season, more than Milwaukee's 469. However, that advantage has not translated into runs consistently, and the pitching staff has struggled compared to Milwaukee's numbers.

Milwaukee Continues Impressive Campaign

The Brewers enter this matchup with a 36-21 overall record and an excellent 20-11 record at home. Milwaukee has won four of its last five games and enters this contest with momentum after a dominant victory over San Francisco. The Brewers also recently won over Houston twice and defeated St. Louis during this successful stretch.

Milwaukee is batting .246 while scoring 284 runs on 469 hits. The Brewers have hit 40 home runs and carry a .334 on-base percentage with a .366 slugging percentage. Their pitching staff has been outstanding, posting a 3.15 ERA and a 1.18 WHIP while limiting opponents to a .216 batting average. Milwaukee pitchers have recorded 552 strikeouts and issued 198 walks.

The biggest advantage for Milwaukee is its pitching. The Brewers own a substantially lower ERA, a lower WHIP, and a much better opponent batting average than San Francisco. Milwaukee has also recorded 552 strikeouts, showing an ability to consistently control games from the mound.

San Francisco Giants vs Milwaukee Brewers Picks and Prediction

San Francisco Giants vs Milwaukee Brewers Pick

  • Pick: Milwaukee Brewers Moneyline

Milwaukee has been the better team throughout the season and enters this matchup with clear advantages. The Brewers have the superior overall record, a strong home record, and significantly better pitching numbers. Milwaukee also owns a commanding 66.2% edge in ESPN's Matchup Predictor and is coming off a 16-2 victory in the series opener. Those factors make the Brewers the preferred side.

San Francisco Giants vs Milwaukee Brewers Total Pick

  • Pick: Take the under if the total is set at 8.5

I would lean toward the under because Milwaukee's pitching staff has been one of the best in this matchup. The Brewers own a 3.15 ERA and a 1.18 WHIP while limiting opponents to a .216 batting average. San Francisco has struggled to score consistently despite a respectable batting average, and Milwaukee's pitching profile suggests run-scoring opportunities may be limited.

Final Score Prediction: Milwaukee Brewers 5 – San Francisco Giants 2

This prediction was written before the completion of game play on Tuesday.