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Seattle Mariners vs. Toronto Blue Jays Prediction and Picks for Sunday, October 19th, 2025

By: Trenton Pruitt Published 10/19/2025, 03:20 AM ET
Mariners vs. Blue Jays Prediction

The Seattle Mariners (3-2) cruised to a 6-2 victory in grand fashion Friday night, and now they’ll need just one win in two tries against the Toronto Blue Jays (2-3) to advance to the World Series. We’ve got you covered with our Game 6 Mariners vs. Blue Jays prediction. Below, I’ll dive into all of the key information for Game 6 and wrap up with picks and predictions. First pitch is scheduled for 8:03 ET from the Rogers Centre in Toronto, ON. Read on for free MLB picks on this game, and check out that link for other game breakdowns.

Mariners Just a Win Away From the World Series

This has been a rollercoaster ride of a playoffs for the Seattle Mariners, but they’ve had more ups than downs, and are now only one victory away from their first AL Pennant and World Series appearance. Things were looking bleak after squandering a commanding 2-0 lead, but the Mariners bounced back with a massive Game 5 victory at home in grand fashion.

It was Eugenio Suarez who emerged as the star on Friday night, even though he’s hitting just .200 in the playoffs. The third baseman blasted a solo home run in the 2nd, and then nuked a grand slam in the 8th to give the M’s a four-run lead in the 6-2 victory. Cal Raleigh also hit a game-tying home run earlier in the 8th. The pitching was sharp once again, and it was Gabe Speier (1.0 IP, 0 ER) who picked up the win in relief. From this point, Seattle is a -295 favorite to advance to the World Series, while sitting at +230 to win the championship.

  • Logan Gilbert (3.44 ERA) heads to the bump for Game 6, and this will be his fourth appearance of the postseason already.
  • The right-hander is 1-0 in the playoffs (11.0 IP), posting a 2.45 ERA and a 1.27 WHIP.
  • Gilbert pitched in Game 2 of this series on Monday, but he lasted only 3.0 innings after allowing three runs (two earned) on five hits and a walk.
  • It was a no-decision in a 10-3 victory.

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Blue Jays Return Home Trailing 3-2

Meanwhile, you have to give credit to the Toronto Blue Jays, as they fought back from an 0-2 deficit in a hostile road environment just to force a return trip home for Game 6. The Jays, who were the American League’s best team at 94-68, now need to win two straight games to punch their ticket back to the World Series for the first time since 1993. The odds are against them, with Toronto is sitting at +241 to advance. They’re +850 to win the World Series.

Game 5 starter Kevin Gausman was solid in the 6-2 defeat, taking a no-decision after throwing 5.2 innings and allowing one earned run. The loss fell on Brendon Little, who gave three earned runs over 0.0 relief innings. Offensively, George Springer and Ernie Clement each notched RBI singles in the losing effort. Toronto out-hit Seattle 7-5, but left eight runners stranded and went just 2-for-11 with RISP. It’s worth noting that Springer (knee) will likely suit up for Game 6.

  • Trey Yesavage will oppose Gilbert on Sunday night, and the 22-year-old rookie has only made five total starts (3 Reg, 2 Post) in his career.
  • The right-hander faced Gilbert in Game 2, and he got lit up for five earned runs on four hits and three walks over 4.0 innings.
  • He took the loss in the 10-3 defeat.
  • During the regular season (14.0 IP), Yesavage went 1-0 with a 3.21 ERA and a 1.43 WHIP.

Mariners vs. Blue Jays Pick

Moneyline Pick for Mariners vs. Blue Jays

  • Toronto Blue Jays Moneyline (-125) (5 units)

The Blue Jays had one mission when they went to Seattle trailing 0-2: win two games and force the series to return to Toronto for another pair of games. Even though Toronto dropped Game 5, the vibes are likely still high since they now have a chance to play two more games in front of their home fans. Toronto was exceptional at home during the regular season, going 54-27 SU. Seattle went just 39-42 SU on the road.

We saw this same pitching matchup in Game 2, and neither starter performed well. I think the Blue Jays will have the edge here in the early innings. They have seen Logan Gilbert well in the past, slashing .307/.352/.495 against him as a team. Specifically, George Springer (5-for-16), Vladimir Guerrero Jr. (6-for-17), and Alejandro Kirk (5-for-14) have done damage against the right-hander. I expect the Jays to take care of business behind their stars in this one.

Over/Under Pick for Mariners vs. Blue Jays

  • Over 7.5 (-110) (5 units)

Typically, I like to bet unders as the series continues, but both of these offenses have been finding so much success that I feel like it’s best to play the over. This same pitching matchup in Game 2 yielded a 10-3 final, and we saw the starters give up eight runs over a combined 7.0 innings.

Furthermore, both offenses have found a ton of success with the long ball in the playoffs. They’re tied for first with 17 home runs in the postseason, each averaging more than 1.5 home runs per game. These bullpens are sharp, but two home run-hitting teams can neutralize the high-powered arms. We’ve already seen this with these offenses in the playoffs. Let’s take the over.

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