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Texas Rangers vs Houston Astros Pick and Prediction, Tuesday, September 16, 2025

By: Cole Shelton Published 09/16/2025, 04:30 AM ET
Texas Rangers vs Houston Astros pick

A pivotal AL West matchup goes down on Tuesday, September 16, at 8:10 p.m. ET as the Texas Rangers take on the Houston Astros, so continue reading for our Rangers vs Astros prediction. This is written before Monday's game has ended.

When it comes to baseball picks, our MLB Predictions are stellar.

Rangers Starting Kelly

Texas is 79-71 and is third in the AL West, two games back of the Astros for the final Wild Card spot. The Rangers are coming off a series win over the Mets. Texas is hitting .237, which ranks 26th, while in the month of September, they are hitting .224.

The Rangers are set to start Merrill Kelly, who's 12-7 with a 3.21 ERA in 30 starts this season. In his last outing, he went 5.2 innings, allowing three runs against the Brewers. In his career against the Astros, he's 0-1 with a 0.93 ERA. Texas has a team ERA of 3.42, which ranks first.

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Astros Holding Onto Playoff Spot

Houston is now 81-69 and in second place in the AL West as the Astros are holding onto a Wild Card spot. Houston is coming off a series win over the Braves, but lost the series finale. Houston is set to start right-hander Christian Javier, who's 1-3 with a 4.78 ERA. In his last outing, he went six innings, allowing 4 runs against the Blue Jays. He's 6-1 with a 3.71 ERA in his career against the Rangers. Houston has a team ERA of 3.86, which ranks ninth.

The Astros are hitting .252, which ranks seventh. While at home, they are hitting .251, and in September are hitting .255. Against Kelly, Caratini hits .333 in 12 ABs,  Walker is 1-for-3, Sanchez hits .167 in 12 ABs with a homer, Correa hits .222 in nine at-bats, and Altuve hits .222 in nine at-bats.

Rangers vs Astros Pick

Spread Pick for Ragners vs. Astros

  • Rangers ML (4 units)

This is a pivotal series for the playoffs, and this is a good spot to take the Rangers on the ML. Kelly has pitched great since being traded to the Rangers, while Javier was hit hard in his last outing. The Astros' offense has also struggled as of late, which will continue to struggle against Kelly here. Given Javier's struggles, take the Rangers on the road to get the win.

Take Rangers ML.

Over/Under Pick for Rangers vs Astros

  • Under (4 units)

The under is a great spot here as these two teams are two of the best under teams in the majors. Texas is 82-66-2 in hitting the under, while the Astros are 75-67-8 in hitting the under this season. Meanwhile, in 10 games this season, the games are averaging 7.2 runs per game, so look for those trends to continue and the under to cash.

Take the under.

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