Toronto Blue Jays vs Chicago Cubs Picks and Prediction for Sunday June 21 2026

By: Kim Smith Published 06/21/2026, 12:35 AM ET
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The Toronto Blue Jays and Chicago Cubs square off on Sunday, June 21, 2026, at Wrigley Field in Chicago, Illinois. First pitch is scheduled for 2:20 PM ET with coverage available on MLB.TV. Toronto enters the matchup with a 37-39 record, while Chicago comes in at 40-36. ESPN Analytics gives the Cubs a slight edge with a 53.2% chance to win compared to 46.8% for the Blue Jays. At the time of this writing the odds were not released. Be sure to check out our free MLB picks.

Starting Pitchers for Sunday's Matchup

Toronto is expected to send Dylan Cease to the mound. Cease has compiled a 4-3 record with an impressive 2.71 ERA and a 1.19 WHIP across 73.0 innings. He has allowed 56 hits while striking out 110 batters and walking 31. Chicago is scheduled to counter with Shota Imanaga, who enters the game with a 4-6 record, a 4.26 ERA, and a 1.06 WHIP over 86.2 innings. He has allowed 70 hits while recording 84 strikeouts, issuing 22 walks, and surrendering 17 home runs.

Toronto Attempts to Recover From a Rough Loss

The Blue Jays enter Sunday's contest with a 37-39 overall record and a 16-21 mark away from home. Toronto has won three of its last five games despite suffering a lopsided 16-2 loss to Chicago in the most recent meeting. Prior to that defeat, the Blue Jays swept a three-game stretch against Boston with victories by scores of 4-3, 3-0, and 6-1. Their other loss during this five-game span came against New York by an 8-3 score.

Toronto has produced a .249 team batting average while scoring 308 runs and collecting 634 hits. The Blue Jays have hit 75 home runs and carry a .312 on-base percentage with a .391 slugging percentage. On the pitching side, Toronto owns a 4.11 ERA and a 1.30 WHIP while holding opponents to a .242 batting average. The staff has recorded 670 strikeouts and issued 259 walks.

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One of Toronto's biggest strengths entering this game is its ability to generate contact. The Blue Jays have collected more hits than Chicago while also owning the better team batting average. Their pitching staff also carries a slightly lower ERA than the Cubs, giving Toronto a statistical advantage in several important categories despite the recent blowout loss.

Chicago Seeks Another Offensive Outburst

The Cubs enter this matchup with a 40-36 overall record and a strong 23-16 mark at home. Chicago has won three of its last five games and comes into Sunday with momentum after a dominant 16-2 victory over Toronto. The Cubs also picked up wins over Colorado by scores of 8-6 and 5-4 during this stretch. Their losses came against Colorado and San Francisco.

Chicago has posted a .243 batting average with 360 runs scored, 630 hits, and 88 home runs this season. The Cubs own a .336 on-base percentage and a .401 slugging percentage. Their pitching staff has recorded a 4.23 ERA and a 1.24 WHIP while limiting opponents to a .239 batting average. Chicago pitchers have accumulated 596 strikeouts against 230 walks.

The Cubs' greatest advantage has been their ability to score runs. Chicago has crossed the plate 360 times this season compared to Toronto's 308 runs. The Cubs also hold the edge in home runs, on-base percentage, and slugging percentage, showing a lineup capable of creating offense in multiple ways.

Toronto Blue Jays vs Chicago Cubs Picks and Prediction

Toronto Blue Jays vs Chicago Cubs Pick

  • Pick: Blue Jays Moneyline

Toronto enters this matchup with the advantage on the mound. The Blue Jays also hold the better team batting average and slightly stronger pitching numbers overall. While Chicago is coming off a dominant victory, the starting pitching matchup favors Toronto, making the Blue Jays the preferred side in the series finale.

Toronto Blue Jays vs Chicago Cubs Total Pick

  • Pick: Under 8.5

I like the under in this matchup. Toronto's starting pitcher carries a 2.71 ERA and has recorded 110 strikeouts in 73.0 innings. While the previous game produced plenty of offense, the presence of a high-quality starter on the mound for Toronto creates the potential for a much lower-scoring contest on Sunday afternoon.

Final Score Prediction: Blue Jays 4 – Cubs 3

This prediction was written before the completion of game play on Saturday.

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