Toronto Blue Jays vs. Tampa Bay Rays Picks and Predictions, Wednesday September 17, 2025
The AL East has been a dogfight all season long, and with the final few weeks of the season upon us, we'll see another blockbuster showdown with our Toronto Blue Jays vs. Tampa Bay Rays prediction.
The Toronto Blue Jays (89-62) have been baseball's hottest team in the second half, and with a slim lead in the division, they've got several reasons to try and keep their momentum going into the postseason.
On Wednesday, they take on the Tampa Bay Rays (73-78), a team that has been uncharacteristically poor in 2025, and with their season seemingly over, this is a team that will try to cause some chaos in the AL East over the coming weeks. Read on to see our Toronto Blue Jays vs. Tampa Bay Rays prediction.
Expected pitching matchup: RHP Kevin Gausman vs. LHP Ian Seymour.
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Can the Jays keep another long winning streak going?
In the second half, the Toronto Blue Jays have gone on one lengthy winning streak, and coming into this matchup, they've got another going as they lead the American League East by five games on the back of a six-game win streak. This season, the Blue Jays' offense ranks first in team average and fourth in total runs scored, and with a respectable team ERA of 4.13 and some exciting names joining the big league ranks, this could be a huge season in Toronto.
Taking the mound here for Toronto will be star right-hander Kevin Gausman, who has put together a very solid 3.44 ERA through 29 starts this season, with the 34-year-old striking out an impressive 171 hitters across 177.1 innings of work. Last time out for the Blue Jays was a big win over these Rays, with five different Jays knocking in runs in this one as they rode 4.0 solid innings from Jose Berrios to the dramatic 6-5 victory.
Can the Rays avoid the sweep in this one?
The Tampa Bay Rays have found ways to win in recent times, but in 2025, that simply hasn't been the case, as the team has gone just 38-38 at home this season, falling to fourth place in the American League East, 16 games back of the division leaders. Despite the struggles, the Rays pitching staff has been solid again, ranking 12th in the league with a 3.88 team ERA on the season, and with the offense ranking 14th in baseball in total runs, it's mind-boggling to see them struggle the way that they have.
Tampa Bay will turn to young lefty Ian Seymour in this series finale, with the 26-year-old compiling a 3.16 ERA over 16 appearances in his rookie campaign, with 52 strikeouts in 42.2 innings of work, showing that he could be a key piece for them moving forward. Last time out for the Rays was a tough loss to these Blue Jays, with Ryan Pepiot giving up four earned over 1.2 innings of work as three hits to Tristan Gray simply weren't enough, with the team ultimately falling 6-5.
Toronto Blue Jays vs. Tampa Bay Rays pick
Money Line Pick for Blue Jays vs. Rays
- Toronto -130 (5 units)
Despite the Tampa Bay Rays going 7-3 in the last 10 head-to-head meetings with their AL East rival, the Blue Jays have come away winners in the two games to start this series, and with the edge on the mound in this one, they could complete a sweep here.
On top of that, Toronto has won six straight games and seven of their last 11 games played on the road, and with the team desperate to stay atop the AL East, expect another hard-fought win for the Blue Jays.
Over/Under pick for Blue Jays vs. Rays
- Under 9 (4 units)
While there were 11 runs scored in the last meeting between these two teams, the under is 6-4 in their last 10 head-to-head encounters, with four or less runs scored in three of their past four meetings heading into Tuesday's game.
For the Blue Jays, the under sits at 7-3 in their last 10 overall games, with just 26 runs allowed during that time, and for the Rays, the under comes in at 5-5 in their past 10, with four or less runs scored in six of them, and no more than five scored in any of those 10.
Keep it simple, take the under.