Cleveland Cavaliers vs. Detroit Pistons, Preview, Odds, Picks and Prediction, Monday, October 27, 2025

By: Craig Forde Published 10/27/2025, 10:56 AM ET
Use Code SSWC

A pair of Central Division foes meet on the hardwood Monday night and we’re getting you ready with our Cavaliers vs. Pistons predictions. Cleveland (1-1 SU, 1-1 ATS) got their first win of the season on Friday night, 131-124, as -11.5 favorites at Brooklyn. Detroit (1-1 SU, 1-1 ATS) won in Houston on Friday, 115-111, as +6.5 underdogs. Tipoff from Little Caesars Arena is scheduled for 7:00 EST and if you’re struggling to pick winners, we have the best NBA Predictions available.

(This game was published prior to the conclusion of Sunday’s games.)

Cavaliers bounce back in Big Apple

The Cavaliers spent the first two games of their season making the rounds in New York City. After losing to the Knicks by eight on Wednesday, they rebounded in Brooklyn behind an offensive effort that saw them score 29 points in each of the first three quarters. Cleveland shot 53.7% in their win, and through two games, the team shot 50% from the field with an average of 18.5 three-pointers. They are 14th in the league with a 1.66 assist-to-turnover ratio, and the Cavs' bench averaged 30.5 points per game. Donovan Mitchell led the team with 35 points on Friday, his second straight 30+ point effort. The guard was shooting 50% heading into Sunday’s action. Lonzo Ball averaged 23 minutes off the bench in the first two games and was leading the club with seven assists a night.

On defense, the Cavaliers have allowed their opponents to score 121.5 points per game, 23rd in the league, and shoot 47.3% from the field. They’ve allowed 16.5 threes a game, and teams are grabbing 44.3 rebounds, compared to their 34 boards per game. Cleveland’s defense is averaging 11 steals and 4.5 blocks, which has led to 16 turnovers from their opponents each game. Through two games, Evan Mobley was averaging eight rebounds and 1.5 blocks per game. Mitchell was leading the club with 2.5 steals a night.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that StatSalt may use third-party services to process my data.

Team notes

  • In their first two games, Cleveland averaged 41 points in the third quarter but only 23.5 in the fourth.
  • Forward De’Andre Hunter, who has yet to play this season due to a knee injury, was questionable for the team’s game on Sunday.
  • Guards Darius Garland (toe) and Max Strus (foot) remain out until at least the end of the month.

Pistons get engine revved

Like their Monday night opponent, the Pistons also spent the first two games of their season on the road before opening up their home digs on Sunday. In Friday’s win over Houston, they led 63-56 at halftime and held on late. They shot just 46.7% in the win and hit 16 threes. This year, Detroit’s offense has been shooting 45.5% from the field while averaging 11.5 threes per game. They ranked third in the league with a 1.96 assist-to-turnover ratio and turned the ball over 13.5 times a night. Cade Cunningham scored 23 on opening night and 21 in Friday’s win, despite shooting 37.5% from the field. After two games, the forward led the team with 22 points and 9.5 assists per game. Ronald Holland II was shooting 52.9% and averaging 15 points per game off the bench, the second-highest average on the team.

Defensively, the Pistons allowed an average of 113 points, seventh in the league, and opponents were shooting 41.8% from the field with 10.5 threes against them. They’ve been slightly outrebounded, 47.5-47 per game. Detroit has coaxed 15 turnovers a day from its foes by way of seven steals and 10.5 blocks per game. Five players averaged over five rebounds in the first two games, with Tobias Harris leading the pack with 8.5 rebounds per game. Isaiah Stewart has come off the bench to average three blocks per game to go with his 12 points a night.

Team notes

  • Through two games, Thompson was shooting 58.3% from the field.
  • Guard Jaden Ivey is out until late November.
  • Center Jalen Duran was ejected from Friday’s game after getting into it with Houston’s Amen Thompson.

Cavaliers vs. Pistons Picks

Spread Pick for Cavaliers vs. Pistons

  • Detroit +1.5 (5 units)

The Cavaliers won three of four meetings straight up between the two teams last season. The Cavs come into this matchup, as they have all season, banged up. They’ve been without two starters and will be without at least one of them in this one, as well as a meaningful depth piece. Their win on Friday came against a bad Nets team, and even then, they won by just five points. On top of that, they have to play Milwaukee as home on Sunday and then travel to Detroit following a 6:00 EST game. The Pistons also play on Sunday, but at 2:00 EST and at home, so they’ll be sitting back resting before the Cavs even suit up on Sunday. Cunningham has turned into a solid leader for this young Pistons core and at home, he’ll put them on his back if he has to. Detroit is 2-0 ATS in the last two games between the teams and they won their last meeting by 11 points at home.

Take the Pistons to cover.

Over/Under Pick for Cavaliers vs. Pistons

  • Under 228.5 (4 units)

In four games between the division rivals last season, they averaged a combined 225.8 points per game. The Cleveland offense had a tough season opener, but they bounced back on Friday with a 131-point effort. The Cavs have plenty of guys who are unafraid to put up the three, so they can light things up in a hurry. They’ve also been ninth in the league in pace through two games, per DunksandThrees.com, averaging 105 possessions per 48 minutes. Detroit is 15th in pace, averaging 102.5 possessions per 48 minutes. They are shooting the ball okay enough and were able to find the right long-range shots in their latest effort. The under is 8-2 in the last ten games between the teams.

Take the under.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Review
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Review
Requirement New Users – Bet $5 Get $200 in Bet Reset Tokens for 5 Days. (Up to $1,000 Bet Reset Tokens)
Cashable No
Fanatics

10 x $100 bet match in FanCash

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Fanatics Review
Cashable No
>

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.