Detroit Pistons vs Philadelphia 76ers Picks and Predictions for Sunday, October 25, 2026

Detroit and Philadelphia have each opened the season with two wins, setting up an early meeting between unbeaten Eastern Conference teams. The Pistons visit the 76ers at Xfinity Mobile Arena on Sunday at 7:30 pm ET on NBA League Pass. Detroit is 2-0, first in the Central Division, after beating Miami 128-111 on Friday. Philadelphia also stands 2-0, tied for first in the Atlantic, after Thursday's 114-106 home win over Cleveland. Both offenses have had encouraging moments, but the Pistons have scored more through two games. Cash in a big winner with our free NBA picks.

Detroit Pistons Have Spread the Scoring Around

Detroit has beaten Boston and Miami, and the two wins looked rather different. The Pistons opened with a 121-113 victory over the Celtics, getting 22 points apiece from Cade Cunningham and Jalen Duren. Against Miami on Friday, John Collins led the scoring with 23 while Paul Reed supplied 19 off the bench. Detroit won 128-111 despite Cunningham scoring only 16. Across those games, the Pistons are averaging 124.5 points and allowing 112. They've also pulled down 51 rebounds per game and shot 49.1% from the field.

Duncan Robinson and Cunningham share Detroit's scoring lead with 19 points per game, while Cunningham also averages eight assists. Collins has contributed 14.5 points, and Reed has added 12.5 points and a team-high 8.5 rebounds. Duren is averaging 13 points and 7.5 rebounds, although he played only 10 minutes in Miami. The Pistons are averaging 30.5 assists and six blocks, and they knocked down 18 three-pointers Friday after making 15 in their opener. Thompson and Duren both carry questionable injury designations.

Injuries: Ausar Thompson is questionable with an undisclosed issue, and Jalen Duren is questionable with a thigh injury.

Philadelphia 76ers Have Started With Two Tight Wins

Philadelphia has made a good start to the season without putting up particularly big scores. The 76ers opened with a 106-100 victory at New York, then returned to Philadelphia on Thursday and defeated Cleveland 114-106. Neither game was decided until the final stages, but the 76ers came away with both wins. They've scored 220 points in two games while allowing 206. Philadelphia has also collected 44.5 rebounds and 26 assists per contest. The shooting hasn't been great at 43.6%, but the defense has helped make up for it.

Tyrese Maxey has scored 60 points through two appearances, including enough baskets to give him a 50% shooting percentage. He's also averaging 5.5 assists and 2.5 steals. Jaylen Brown has chipped in with 20 points and eight rebounds per game, while Joel Embiid is contributing 18.5 points, nine rebounds and 1.5 blocks. LeBron James has pulled down 19 rebounds and handed out 12 assists in two games, giving him averages of 9.5 and six. James is also scoring 15.5 points per contest, although he's questionable for Sunday with a back injury.

Injuries: Tacko Fall and Dominick Barlow are out, and Ariel Hukporti is out for the season. LeBron James and Dean Wade are questionable.

Key To The Game

Detroit's ball movement has produced 30.5 assists per game, but Philadelphia has allowed just 103 points per contest. The Pistons need Cunningham creating chances, while the 76ers need Maxey's scoring and another solid defensive performance.

Detroit Pistons vs Philadelphia 76ers Game Pick

• Philadelphia 76ers

Detroit has scored at least 121 points in both wins, but Philadelphia's defense presents a tougher assignment. The 76ers have held New York to 100 and Cleveland to 106, while Maxey has averaged 30 points. Detroit's depth has been useful, although Thompson and Duren are questionable. Philadelphia has more reliable defensive results so far and gets another strong scoring night from Maxey. The 76ers stay unbeaten with a home victory.

Detroit Pistons vs Philadelphia 76ers Over/Under Pick

• Over

Detroit has scored 121 and 128 points in its first two games, with plenty of help beyond Cunningham. Philadelphia has been slower scoring, but Maxey is averaging 30 points and the 76ers have several other capable scorers. The Pistons are also allowing 112 points per contest, creating openings for Philadelphia. Detroit keeps pushing the pace and gets enough production to lift the combined score. The over is the play Sunday.