Memphis Grizzlies vs San Antonio Spurs Prediction and Picks - November 18, 2025

By: Dean Whitaker Published 11/18/2025, 07:10 AM ET
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Pro hoops action on Tuesday evening, and we have a Memphis Grizzlies vs San Antonio Spurs prediction locked and loaded for you. Memphis comes in off a 108-100 loss to the Cavaliers on the road, which drops them to 4-10 on the year. The Spurs come in at 9-4 on the year and off a 123-110 home win over the Kings. Memphis won three of the four meetings a year ago. Read on to see our Grizzlies vs Spurs prediction.

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Ja Morant Out At Least Two Weeks

The Grizzlies enter this game at 4-10 after dropping their last contest 108-100 at Cleveland. Ja Morant suited up but played only six minutes before leaving, underscoring the impact of his calf injury that will now sideline him for at least two weeks. Without their primary playmaker, Memphis struggled to generate consistent offense and fell short despite keeping the game competitive. Overall, the team has been inconsistent on both ends of the floor, ranking 25th in scoring at 111.9 points per game while allowing 119.9 points per game, which places them near the bottom of the league defensively.

Jaren Jackson Jr. has been one of the team’s most reliable contributors, averaging 17.9 points and 5.2 rebounds while shooting 47.8% from the field and 37.7% from three. Supporting him, Santi Aldama has chipped in 12.6 points and nearly seven rebounds per game, while wing options like C. Coward (14.0 PPG) and K. Caldwell-Pope (7.9 PPG) provide secondary scoring. Jock Landale has been efficient in the frontcourt, shooting 54.4% from the field and 45.7% from deep, while rookie Zach Edey showed promise in his lone appearance with 13 points and seven boards. Still, the team’s overall shooting struggles—just 43.0% from the field and 32.9% from three—have limited their ability to keep pace with opponents.

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Defensively, Memphis has had difficulty containing opponents, allowing 48.3% shooting from the field and ranking 25th in rebounds allowed at 47.1 per game. While they’ve been solid at defending free throws (holding opponents to 76.7%), their perimeter defense has been vulnerable, giving up 36.3% from beyond the arc. With Morant sidelined, the Grizzlies will need Jackson Jr. and Aldama to shoulder more of the scoring load while tightening up defensively. Against San Antonio, Memphis must find ways to improve efficiency and limit turnovers if they hope to snap their skid and stay competitive

Spurs Continue Solid Start

The Spurs enter this game at 9-4 after a 123-110 home win over Sacramento on November 16. That victory highlighted their offensive firepower, as San Antonio continues to lead the league in scoring at 128.8 points per game. Even in recent close losses to Golden State and the Lakers, the Spurs have shown they can compete with top-tier teams thanks to their balanced attack and ability to rebound. Their offense ranks fourth in field goal percentage at 49.7% and second in rebounds per game at 49.7, giving them a strong foundation to dictate pace and control possessions.

Victor Wembanyama has been the centerpiece of the Spurs’ success, averaging 26.2 points, 12.9 rebounds, and an impressive 3.6 blocks per game while shooting over 50% from the field. Rookie Stephon Castle has emerged as a dynamic backcourt presence, contributing 17.3 points and 7.5 assists per game, while Devin Vassell adds 13.8 points with steady perimeter shooting. Keldon Johnson has provided interior scoring and rebounding at 11.1 points and 6.2 boards per game, while Harrison Barnes has been efficient with 12.1 points on 54.2% shooting. Depth contributions from players like Jordan Champagnie and Davion Harper have further bolstered San Antonio’s rotation, keeping the offense versatile and difficult to defend.

Defensively, the Spurs remain a work in progress. They allow 121.5 points per game, ranking 23rd, and opponents have shot 38.9% from three against them, exposing their perimeter defense. However, their overall field goal defense is strong at 44.7%, ranking fifth, and their ability to protect the rim has been anchored by Wembanyama’s shot-blocking presence. Free-throw defense has been a weakness, with opponents converting 82.3%, but San Antonio’s rebounding edge and offensive efficiency often offset those lapses. Against Memphis, the Spurs will look to exploit the Grizzlies’ shooting struggles and capitalize on Morant’s absence, aiming to extend their winning record with another high-scoring performance.

Memphis Grizzlies vs San Antonio Spurs Pick

Grizzlies vs Spurs Spread Pick

  • Memphis +6 (1 Units)

Memphis looks like a solid play catching six points in this matchup. Even without Ja Morant, who exited early in the loss to Cleveland and will now miss time with a calf injury, the Grizzlies have shown they can stay competitive. Jaren Jackson Jr. continues to anchor the offense with 17.9 points per game, while Santi Aldama and C. Coward provide reliable secondary scoring. Memphis also benefits from a strong free-throw percentage at 82.1%, ranking eighth in the league, which helps them convert opportunities late in games. Against a Spurs team missing Victor Wembanyama, the Grizzlies should be able to keep the margin close with balanced contributions across the roster.

San Antonio’s offense has been explosive, leading the league at 128.8 points per game, but losing Wembanyama removes their most dominant interior presence. Without his rebounding and shot-blocking, the Spurs’ defense—which already allows 121.5 points per game—becomes more vulnerable. Memphis, despite its shooting struggles, has enough frontcourt depth with Jackson Jr., Aldama, and Jock Landale to exploit that absence. Given the Spurs’ defensive lapses and the Grizzlies’ ability to grind out possessions, taking Memphis +6 offers value as they should be able to hang around and potentially push this game down to the wire.

Grizzlies vs Spurs Over/Under Pick

  • Under 232.5 (3 Units)

The Under 232.5 makes sense here with both teams missing their stars, as Ja Morant and Victor Wembanyama are sidelined by calf injuries. Memphis has struggled offensively, ranking 29th in field goal percentage at 43.0% and 28th in three-point shooting at 32.9%, while San Antonio’s defense—though inconsistent—still holds opponents to 44.7% shooting overall. Without Wembanyama’s scoring and rim protection, the Spurs may lean more on perimeter play and ball movement, which could slow the pace. Combined with Memphis’ shooting inefficiency, this matchup sets up for a lower total than expected, keeping the scoreline under 232.5.

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