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Minnesota Timberwolves at New York Knicks Picks and Prediction for Wednesday, November 5, 2025

By: Arthur Reyes Published 11/05/2025, 10:40 AM ET
Trail Blazers vs Knicks

The Minnesota Timberwolves are heading to Madison Square Garden on Wednesday evening to take on the New York Knicks in nonconference action for our Timberwolves vs. Knicks prediction. The Timberwolves are sixth in the West with a 4-3 record as they are on a two-game winning streak as they are coming off a 125-109 road win over the Brooklyn Nets on Monday. The Knicks are sixth in the East with a 4-3 record and are also on a two-game winning streak after coming off Monday’s 119-102 home win over the Washington Wizards. This will be the first of two games against one another as they do not play again until a few days before Christmas. Half-court to transition — NBA picks for Minnesota Timberwolves at New York Knicks with key factors.

Timberwolves Looking to Win Without Edwards

The Minnesota Timberwolves are looking to continue playing well as they are coming off a 125-109 road win over the Brooklyn Nets during their most recent game. The T-Wolves shot the basketball at an incredible level as they were able to go 44-of-78 (56.4%) from the field, 14-of-35 (40.0%) from distance, and 35 trips to the free-throw line. Shooting guard Donte DiVincenzo led the offense in this game, as in 30 minutes he posted 25 points, nine rebounds, five assists, and one block. This was a game where the defense played well, as they allowed the Nets to post a team shooting split of 40.4/30.0/65.8.

The Minnesota Timberwolves are holding their own offensively as they are tied with the Orlando Magic for 15th in the league with 116.9 points per game while having a 49.8 shooting percentage, 40.2 3-point percentage, and 74.7 free-throw percentage. Their defense has been a bit better than average in the NBA, though, as they rank 11th with 115.6 points per game allowed while allowing their opponents to shoot 46.6% from the field and 34.8% from beyond the arc thus far.

Injury Report for Minnesota

  • Shooting guard Anthony Edwards: Hamstring (OUT)

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Knicks Looking to Get Hot

The New York Knicks are coming off a solid 119-102 home win over the Washington Wizards last time out. The team was able to play at an outstanding level offensively as they finished shooting 44-of-94 (46.8%) from the field, 15-of-41 (36.6%) from beyond the arc, and attempted 20 free throws. Center Karl-Anthony Towns was able to lead the way as he finished with 33 points, 13 rebounds, five assists, and two steals in 30 minutes of action. Their defense struggled a bit as Washington shot 38-of-81 (46.9%) overall, 13-of-35 (37.1%) from three, and allowed 19 free throws.

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The New York Knicks are doing a decent job offensively as they are tied with the Sacramento Kings for 17th in the NBA with 116.3 points per game while shooting 43.5% from the floor, 36.5% from the 3-point line, and 84.7% from the free-throw line. Their defense has been playing well thus far as they are in eighth place with 113.6 opposing points per game while allowing 48.3% overall and 39.6% from beyond the arc.

Injury Report for New York

  • Center Mitchell Robinson: Ankle (OUT)

Minnesota Timberwolves at New York Knicks Pick

Spread Pick for Timberwolves vs. Knicks

  • New York Knicks to cover (4 units)

The ability to grab rebounds throughout the season gives a team a good chance to be successful, and there is a gap here. The Knicks are fifth in the NBA with a 53.3 total rebounding rate, while the Timberwolves are 17th with a 49.3 rebounding percentage so far. Without Anthony Edwards playing a role as he is out with an injury, the Knicks have arguably three of the top four players in the game. Go with the Knicks to cover the spread in their own building as the better bet.

Over/Under Pick for Timberwolves vs. Knicks

  • UNDER (5 units)

The lack of scoring for the Timberwolves could be on display, as without Edwards on the court, this offense looks a bit different. Both sides are playing at a more methodical pace this season as Minnesota is 23rd with a 99.57 pace, while New York is 22nd with a 100.21 pace right now. The under has hit in six of the previous 10 games against one another, so go with the UNDER here as well.

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