Portland Trail Blazers vs Memphis Grizzlies Prediction and Picks - December 7, 2025

By: Dean Whitaker Published 12/06/2025, 10:39 PM ET
Jaren Jackson Jr.looks to lead the Grizzlies over the Trail Blazers
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Sunday evening on the NBA hardwood, and we have a Portland Trail Blazers vs Memphis Grizzlies prediction locked and loaded for you.  Portland comes in off a 122-116 road loss to Detroit to fall to 9-14 on the year. Memphis comes in at 10-13 on the year and they are off a 107-98 home win over Memphis. The Grizzlies took two of the three meetings a year ago. Read on to see our Trail Blazers vs Memphis prediction.

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Portland Falls Short In Detroit

Portland’s most recent game was a 122–116 loss at Detroit on December 5, where Deni Avdija poured in 35 points and Robert Williams III grabbed 14 rebounds, but the Blazers couldn’t hold off Cade Cunningham’s late surge. Portland led for stretches and had balanced scoring, yet the Pistons closed on a 19–8 run to hand the Blazers their fourth loss in five games.

Offensively, Portland averages 118.3 points per game (14th), but their efficiency lags with a 44.4% field‑goal percentage (29th) and just 32.9% from three (30th). Avdija has been the focal point, averaging 26.2 points, 7.2 rebounds, and 6.2 assists, while Jerami Grant adds nearly 20 points per game with strong perimeter shooting. Shaedon Sharpe and Caleb Love provide secondary scoring, though the team’s reliance on free throws (79.7% FT, 12th) has been critical in staying competitive. Portland’s rebounding is a strength at 46.0 boards per game (4th), giving them second‑chance opportunities despite shooting struggles.

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Defensively, the Blazers have struggled, allowing 120.7 points per game (25th) and opponents to shoot 48.0% (23rd). They’ve been vulnerable at the line, with opponents hitting 80.9% (27th), and while they contest threes decently (36.0% allowed, 12th), their overall defensive consistency has been lacking. Injuries remain a major storyline: Scoot Henderson (hamstring), Jrue Holiday (calf), Matisse Thybulle (thumb), Blake Wesley (foot), and Damian Lillard (Achilles, out for season) have left Portland shorthanded. With Avdija carrying the load, the Blazers will need their role players to step up against Memphis’ size and rebounding.

Grizzlies have won Four Of Last Five

Memphis’ most recent game was a 107–98 win over the Clippers on December 5, where rookie Cedric Coward posted 23 points and 14 rebounds, and Cam Spencer added 17 points with seven assists. The Grizzlies closed on a 9–0 run, locking down defensively in the final minutes to secure their fourth win in five games.

Offensively, Memphis averages 113.4 points per game (23rd) while shooting 44.9% from the field (27th) and 33.8% from three (28th). Jaren Jackson Jr. leads the team at 17.5 points per game, while Coward has emerged as a force inside, averaging 23 points and 14 rebounds over his last 10 games. Spencer has provided a spark from deep, hitting 18 of his last 29 threes, and Vince Williams Jr. has stepped into a playmaking role with multiple 15‑assist games. The Grizzlies rebound at an elite level, pulling down 46.3 boards per game (3rd), which helps offset their shooting inefficiency.

Defensively, Memphis allows 116.1 points per game (13th), holding opponents to 47.3% shooting (17th) and 37.0% from three (22nd). They’ve been strong at the line, limiting opponents to 77.5% FT (7th), and their interior presence with Coward and Jackson Jr. has made them tough to score against in the paint. Injuries remain significant: Ja Morant (calf, day‑to‑day), Brandon Clarke (knee), Ty Jerome (calf), Javon Small (toe), and Scotty Pippen Jr. (toe) are sidelined. Even so, Memphis has found rhythm with Spencer and Coward stepping up, and their recent surge makes them a dangerous opponent for Portland.

Portland Trail Blazers vs Memphis Grizzlies Pick

Trail Blazers vs Memphis Spread Pick

  • Memphis -1.5 (5 Units)

Memphis -1.5 feels like the right side because the Grizzlies are coming off a 107–98 win over the Clippers on December 5, where rookie Cedric Coward dominated with 23 points and 14 rebounds and Cam Spencer added 17 points with seven assists. That game showed how Memphis can close late, finishing on a 9–0 run to seal it, and their rebounding edge continues to be a major weapon. With Jaren Jackson Jr. anchoring the frontcourt and Spencer providing perimeter shooting, Memphis has found a rhythm despite injuries to Ja Morant and Brandon Clarke. Portland, meanwhile, just dropped a 122–116 decision to Detroit, and their defensive issues — allowing over 120 points per game — make them vulnerable against a Grizzlies team that thrives on second‑chance opportunities.

The other angle is Memphis’ balance and depth compared to Portland’s reliance on Deni Avdija and Jerami Grant. The Blazers average 118.3 points per game, but they shoot just 44.4% from the field and rank near the bottom in three‑point percentage at 32.9%. Memphis counters with 46.3 rebounds per game (3rd in the NBA), giving them control of the glass and extra possessions. Defensively, the Grizzlies allow 116.1 points per game, but their ability to contest shots inside and limit free‑throw damage (opponents just 77.5% FT) gives them an edge. With Coward emerging as a reliable scorer and Spencer stretching defenses, Memphis has the tools to outlast Portland and cover the short spread.

Trail Blazers vs Memphis Over/Under Pick

  • Over 235.5 (4 Units)

The Over 235.5 looks appealing in Trail Blazers–Grizzlies because both teams lean heavily on pace and offensive volume while struggling to consistently get stops. Portland just dropped a 122–116 game to Detroit, and they’ve been giving up 120.7 points per game while still scoring 118.3 per game, a profile that screams shootout potential. Memphis, meanwhile, beat the Clippers 107–98 but averages 113.4 points per game and rebounds at a top‑three rate, which fuels extra possessions. Neither team shoots particularly well from deep, yet their rebounding and free‑throw efficiency keep scoring totals high. With Portland’s defensive lapses and Memphis’ ability to control the glass and push tempo, this matchup has the right ingredients to clear the 235.5 total.

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