San Antonio Spurs at New Orleans Pelicans Picks and Prediction for Friday, October 24, 2025

By: Patty Reyes Published 10/24/2025, 03:10 AM ET
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The San Antonio Spurs visit the New Orleans Pelicans at Smoothie King Center on Friday at 8:00 PM ET. San Antonio opened its season with an impressive 125-92 road win over Dallas, while New Orleans fell 128-122 at Memphis in a high-scoring opener. See the floor better with NBA picks for the San Antonio Spurs at the New Orleans Pelicans.

Spurs Look To Stay Hot After Dominant Opener

San Antonio opened its season with a statement, defeating the Mavericks 125-92 behind a 40-point, 15-rebound performance from Victor Wembanyama. The Spurs shot an impressive 57.5% from the field and dominated the boards with 50 rebounds. The balanced attack featured Stephon Castle adding 22 points and rookie Dylan Harper contributing 15 off the bench. The Spurs also forced 10 steals.

The Spurs’ opening night numbers are from just one game, but may be signs of what’s to follow. They posted 24 assists on 48 made field goals and controlled the pace, outscoring Dallas by double digits in each of the final three quarters. The defense in the paint stood out as they blocked five shots and held the Mavericks to just 92 points. If San Antonio maintains that strong a defense and Wembanyama continues to control both ends, the Spurs will be tough to beat on Friday.

San Antonio’s most recent win also marked a statement about its depth in the frontcourt. Wembanyama’s inside scoring was dominant, but Castle and Harper provided additional points, allowing the Spurs to spread the floor. The team’s rebounding and defense were clear improvements from last year’s inconsistent play. Against New Orleans, those same trends will be critical in limiting Zion Williamson’s attempts to score at the rim and keeping the Pelicans off the glass.

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Injuries could impact the Spurs. De’Aaron Fox and Jeremy Sochan are both ruled out until early November, while Kelly Olynyk and Lindy Waters III are game-time decisions. The absence of Fox removes a key scorer and playmaker.

Pelicans Seek First Win Of The Season

New Orleans dropped its opener 128-122 in Memphis despite strong offensive production. The Pelicans shot 45.9% from the field and totaled 47 rebounds, led by Zion Williamson’s 27 points, nine rebounds, five assists, and five steals. Herbert Jones, Jordan Poole, and rookie Jeremiah Fears each scored 17 points, showing balanced scoring options behind their star forward. Still, the team’s defense faltered in the third quarter, allowing a 41-22 Memphis surge that decided the game.

Despite the loss, New Orleans’ attack made a statement about how solid it can be on offense. The 122 points scored were an encouraging sign for going forward, particularly in transition. The Pelicans recorded 20 assists and 10 steals, but lapses on defense and foul trouble hurt New Orleans down the stretch. They will need better execution defending the paint against Wembanyama’s size.

The Pelicans will look to improve second-half defensive intensity after allowing Memphis to shoot too many uncontested shots in the third quarter. Williamson’s all-around effort shows he’s healthy, but the team must play more consistent perimeter defense. The 45.9% shooting mark was solid to start the season, yet defensive rebounding allowed Memphis multiple second-chance points.

Injuries remain a concern for New Orleans. Dejounte Murray and Kevon Looney are both sidelined, while Yves Missi and Karlo Matkovic are listed as game-time decisions.

San Antonio Spurs at New Orleans Pelicans Pick

Spread Pick for Spurs vs. Pelicans

  •  San Antonio Spurs +3 (4 Units)

San Antonio enters this matchup with momentum after routing Dallas, while New Orleans struggled in its opening night loss in Memphis. The Spurs’ 57.5% shooting and 50 rebounds demonstrate that the revamped roster is capable of producing. Wembanyama’s presence inside, combined with Castle’s scoring touch, gives San Antonio matchup advantages against a shorthanded Pelicans roster. With the Pelicans adjusting to injuries and the defense still trying to gel, the Spurs’ offense and strong rebounding make them a solid play to cover the spread and possibly win outright.

Over/Under Pick for Spurs vs. Pelicans

  •  Over 247.5 (5 Units)

Both teams showcased high-paced offenses in the openers, combining for nearly 250 points in total. San Antonio’s 125-point performance featured excellent ball movement and shot selection, while New Orleans posted 122 points. With Wembanyama, Williamson, and multiple young scorers on both sides, the tempo should remain quick. Given the early-season defensive adjustments and shooting from both teams, another fast, high-scoring contest is likely. The Over is a strong pick based on both clubs’ first games of the season.

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