New York Yankees vs. Minnesota Twins Prediction and Picks - September 15, 2025

By: Caleb Davis Published 09/15/2025, 10:40 AM ET
Yankees vs Twins Prediction
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The Minnesota Twins will host the New York Yankees at Target  Field, and we have you ready to go with the Yankees vs the Twins prediction.

Opening Pitch is slated for 7:40 PM Eastern, as the Yankees look to solidify their spot in the postseason. Read on for the Yankees vs Twins prediction and more free MLB picks.

Yankees Unable To Pull Off Sweep

New York found itself in a hole early, trailing 0-6 after the first inning. The Yankees did all the rest of the scoring, but their four runs on seven hits weren't enough to get the job done. Aaron Judge led the way as he was the only Yankee to log multiple hits, and he added a home run in the 5th. The Yankees struck out 16 times in the contest. Will Warren got the start, and over five innings, he struck out two and allowed six runs.

RHP Carlos Rodón is slated to take the mound for the New York Yankees. Rodón has made 30 starts, posting a 16-8 record with a 3.11 ERA over 176.1 innings pitched. He has struck out 186 batters, issued 52 walks, producing a 1.07 WHIP. While he's been more vulnerable on the road this season, Rodón is tossing some of his best in nighttime games, where he is also holding opponents to under .200 at the plate.

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On the road this season, Rodón holds the following splits:

  • ERA: 3.34
  • Opponent Batting Average (OBA): .219
  • BB/K Ratio: 0.43

New York enters this contest averaging 6.5 runs per game, which lands them at 2nd in the league. The Yankees have been strong at the plate and are currently sitting in the top 10 in collective batting average. That average has slipped a bit at home, and fewer than half of their home runs and extra-base hits are coming out of Yankee Stadium. The Yankees have hit much stronger in afternoon games, and they have also seen their home run rate climb. New York still leads the league in home runs per game and is hovering around the top 10 in terms of walks per game. This has continued to allow them to drive runners home at a high rate.

Twins Struggle At Home

Minnesota was unable to match the Arizona bats as they fell short in a 4-6 final. Arizona finished with seven hits, with two players logging multiple hits at the plate. James McCann led the way with two hits, four RBIs, and a home run. Minnesota struck out 13 times on the afternoon. Nabil Crismatt got the start, and over five innings, he struck out four and allowed no earned runs.

RHP Simeon Woods Richardson is slotted to take the hump first for Minnesota. Woods Richardson has made 19 starts, posting a 6-4 record with a 4.58 ERA over 94.1 innings pitched. He’s struck out 84 batters while issuing 41 walks, resulting in a 1.39 WHIP. He's been his most vulnerable in night games, but Woods Richardson has retired 13 batters over his last two starts. He notched seven in his last start at home.

At home, Woods Richardson holds the following splits:

  • Home Record: 4-2
  • ERA: 3.42
  • BB/K: 0.38

Minnesota enters this contest averaging 3.69 runs per game, which lands them at 23rd in the league. The Twins have struggled with consistency this season and have fallen to 23rd in overall batting average. That average has been stronger at home, however. However, more than half of their doubles come away from Target Field. The Twins have been hitting a bit better in afternoon games this season, but home runs have been few and far between.

Yankees vs. Twins Pick

Side Prediction for Yankees vs Twins

  • Yankees ML

New York sits in the top three in terms of overall batting average, and they've continued to hit very well under the lights this season. They also sit atop the league in terms of home runs per game. While the Yankees have been prone to a high strikeout rate, they are also being walked at one of the highest rates in baseball. Rodon has been solid on the mound this season, and we should see his high K rate to continue here, against a volatile Twins lineup.

New York ML

Total Prediction for Yankees vs Twins

  • Over 8.5

As mentioned, the New York bats have been creating contact over the first half of September, and they'll look to stay hot on the road. Minnesota has been vulnerable at the plate, but they sit in the top half of the league in walks received, and they've climbed into the top 10 in terms of home runs per game. On the mound, Minnesota has struggled to get out of innings at times, and when hitters are in position, they've been even more erratic. Expect to see runs here.

Over 8.5

 

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