Denver Broncos vs Carolina Panthers Picks and Predictions for Sunday, November 8, 2026
Denver cannot be stopped from winning right now, downing Kansas City 28-24 last week to secure their fourth straight victory. The Broncos (6-2, 1st AFC West) are off to Charlotte this Sunday. The Panthers (3-4, 1st NFC South) look completely lost after a 27-19 road defeat at Green Bay marked their second consecutive loss. Kickoff at Bank of America Stadium is at 1:00 pm ET on CBS. Denver enters with a mediocre 2-2 road record, while Carolina struggles at home with a 1-2 line. Break down all NFL games with our free NFL picks.
Denver Broncos Riding Four Straight Wins
Kansas City pushed Denver to the absolute limit last week. The Broncos survived 28-24, right after handling Arizona 30-16 and outlasting Seattle in a 17-14 overtime grinder. They also took care of business against the Chargers 23-17. That is four straight checks in the win column following an early setback against San Francisco. Denver is scoring 21.5 points per contest and yielding 20.6.
Bo Nix has thrown for 1,493 yards, nine touchdowns, and three interceptions. He hits 59.6% of his targets. On the ground, J.K. Dobbins has logged 306 yards and three scores, while Jonah Coleman has chipped in 134 yards with two touchdowns. Jaylen Waddle leads the wideouts with 315 yards and two scores, followed closely by Courtland Sutton and his 221 yards. Flipping to the defense, Alex Singleton has racked up 101 tackles, Zach Allen has 4.5 sacks, and Brandon Jones has pulled down two interceptions.
Injuries: RJ Harvey and Tyler Badie are stuck on IR. Talanoa Hufanga, Brandon Jones, and Kris Abrams-Draine are questionable.
Carolina Panthers Searching for a Response
Green Bay completely solved Carolina last Thursday night. That 27-19 defeat was added to a 43-13 blowout loss against Tampa Bay the previous week. Giving up 70 points in two games is a massive problem. Before everything collapsed, the Panthers beat Philly 25-14 and edged Detroit 32-26. They also dropped an earlier 21-18 decision to Cleveland, putting them at 2-3 over their last five games. Carolina scores a solid 25.4 points per night but allows a terrible 27.6.
Bryce Young has recorded 1,921 passing yards, 13 touchdowns, and five picks. He connects at 58.7% but has been dropped for 23 sacks. Chuba Hubbard has run for 540 yards and five scores, picking up 4.6 yards per carry. Tetairoa McMillan has caught 42 balls for 569 yards and two scores, while Jalen Coker has 364 yards and three touchdowns. Defensively, Bobby Okereke has 49 tackles, Devin Lloyd has two picks, and Princely Umanmielen has three sacks.
Injuries: Brady Christensen and Jonathon Brooks are on IR. Torricelli Simpkins III, Damien Lewis, and Bobby Brown III are questionable.
Key To The Game
Everything comes down to protecting the pocket. Denver's defense has generated 23 sacks this year, which perfectly matches the 23 sacks Carolina's line has surrendered. Allen will live in the backfield if the Panthers cannot block. However, Denver's secondary is banged up, and McMillan can exploit those matchups if Young gets any time to throw. Hubbard must run effectively to keep the clock moving and keep Denver's front seven off balance.
Denver Broncos vs Carolina Panthers Game Pick
- Denver Broncos -2.5
Carolina is heading in the wrong direction fast, letting up 70 points over their last two games. Denver knows how to win ugly, grinding out victories against quality opponents like the Chiefs and Seahawks. Nix takes care of the football with a clean 9-to-3 touchdown-to-interception ratio, and his defense will cause serious problems for a Panthers line that cannot protect Young. Carolina has dangerous skill players, but their defensive front cannot stop anybody right now. Trust the hotter team with the better line play to cover this small 2.5-point spread on the road.
Denver Broncos vs Carolina Panthers Over/Under Pick
- Over 43.5
Carolina’s games are turning into absolute track meets, yielding 46 and 56 total points over the last two weeks. Their defense gives up 27.6 points per game, which gives a surging Denver offense a great chance to light up the scoreboard. The Broncos just hung 28 on Kansas City and 30 on Arizona, showing they can score when the matchup is right. Young and Hubbard have enough talent to move the ball against a banged-up Denver secondary. This number sits way too low for a game featuring a bottom-tier Panthers defense. Take the over.