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Houston Texans vs Kansas City Chiefs Prediction and Picks - December 7, 2025

By: Dean Whitaker Published 12/06/2025, 11:59 AM ET
Patrick Mahomes looks to lead the Chiefs over the Texans

It's Sunday Night Football, and we have a Houston Texans vs Kansas City Chiefs prediction locked and loaded for you. The Texans enter this game off a 20-17 road win over the Colts, and they are now 7-5 on the year. Kansas City comes in at just 6-6 on the year, and they are off a 31-28 loss to Dallas on the road. Read on to see our Texans vs Chiefs prediction.

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Houston Grabs Huge Road Win Over Colts

The Texans’ most recent game was a 20–16 win over the Indianapolis Colts on November 30, where C.J. Stroud threw for 276 yards and Nico Collins hauled in five catches for 98 yards, including a key touchdown run on a jet sweep. Houston’s defense held Jonathan Taylor to just 86 rushing yards, sealing their fourth straight victory.

Offensively, Houston has been steady but not explosive, averaging 326.8 total yards per game (18th) and 21.9 points per game (21st). Stroud has thrown for 1,978 yards with 11 touchdowns and six interceptions, while Collins leads the receiving corps with 795 yards and four scores. Rookie running back Woody Marks has chipped in 486 rushing yards, though the ground game ranks just 23rd overall. The Texans have protected the football well, committing only 10 turnovers (7th fewest), which has been critical in their recent surge.

Defensively, Houston has been elite, ranking 1st in total defense (265.7 yards allowed) and 1st in points allowed (16.5 per game). They’re top‑five against both the pass (174.0 yards allowed, 4th) and the run (91.7 yards allowed, 4th). Injuries, however, are notable: LB Jamal Hill (hamstring, out), S Jaylen Reed (forearm, out), CB Kamari Lassiter (foot, questionable), and DT Tim Settle Jr. (foot, IR) headline the list. Will Anderson Jr. (chest/shoulder) and RB Woody Marks (ankle) were limited earlier in the week but are expected to play. Even with those concerns, Houston’s defense has carried them into playoff contention.

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Chiefs Are A .500 Team?

The Chiefs’ most recent game was a 31–28 Thanksgiving Day loss to the Dallas Cowboys on November 27, where Patrick Mahomes threw for 261 yards and four touchdowns but the defense surrendered 457 total yards and failed to record a sack. It was Kansas City’s third loss in four games, dropping them to 6–6 and raising questions about their consistency.

Offensively, Kansas City remains dangerous, averaging 374.8 total yards per game (5th) and 25.4 points per game (9th). Mahomes has thrown for 3,238 yards with 22 touchdowns and seven interceptions, while Travis Kelce continues to be his top target with 719 receiving yards and five scores. Rashee Rice has emerged as a reliable secondary option with 486 yards and five touchdowns, and Kareem Hunt leads the ground game with 515 rushing yards and seven scores. The Chiefs have committed only 8 turnovers (4th fewest), keeping them efficient even in close contests.

Defensively, Kansas City ranks 9th in total defense (306.7 yards allowed) and 7th in points allowed (19.3 per game). They’ve been solid against both the pass (205.8 yards allowed, 12th) and the run (100.9 yards allowed, 9th). Injuries, however, loom large: OT Jawaan Taylor (triceps/knee, doubtful), G Trey Smith (ankle, doubtful), CB Chris Roland‑Wallace (back, out), and WR Nikko Remigio (shoulder, out) headline the report. Mahomes (knee), Isiah Pacheco (knee), and Rashee Rice (hamstring) were all full participants and are expected to play. With offensive line depth tested, Kansas City will need Mahomes’ mobility and quick release to offset Houston’s relentless pass rush.

Houston Texans vs Kansas City Chiefs Pick

Texans vs Chiefs Spread Pick

  • Houston +3.5 (4 Units)

Taking the Texans +3.5 makes sense because their defense has been the best in football, holding opponents to just 265.7 yards per game (1st) and a league‑low 16.5 points per game. In their 20–16 win over Indianapolis, Houston showed how they can dictate tempo by shutting down Jonathan Taylor and forcing Daniel Jones into tough throws. C.J. Stroud has been steady, and while the offense isn’t explosive, it protects the ball well with only 10 turnovers (7th fewest). That kind of efficiency paired with a defense that consistently wins battles up front gives Houston a real chance to keep this game tight against Kansas City.

The other angle is how Houston’s defensive strengths match up against the Chiefs’ offense. Patrick Mahomes is still dangerous, but Kansas City has dropped three of its last four and just gave up 457 yards in a 31–28 loss to Dallas. The Texans rank top‑five against both the run and the pass, which means they’re built to slow down Travis Kelce and force Mahomes into longer drives. With Kansas City’s offensive line banged up and Houston’s pass rush healthy, the Texans have the tools to frustrate the Chiefs. Getting more than a field goal with a team that thrives in low‑scoring, grind‑it‑out games makes Houston +3.5 a sharp play.

Texans vs Chiefs Over/Under Pick

  • Under 42 (5 Units)

The Under 42 feels like the right lean in Texans–Chiefs because both defenses are built to keep scoring in check, and Houston in particular has been dominant, allowing just 16.5 points per game (1st) while holding opponents to 265.7 total yards (best in the NFL). Kansas City’s defense isn’t far behind, ranking 7th in points allowed (19.3) and top‑10 against both the run and the pass, which makes this matchup less likely to turn into a shootout. Even though Patrick Mahomes and C.J. Stroud are capable of big plays, Houston’s style has been to grind games down, as seen in their 20–16 win over Indianapolis, while the Chiefs themselves just lost 31–28 to Dallas in a game where their offense was forced into long drives. With Houston’s defense dictating tempo and Kansas City’s unit strong enough to limit Stroud, this Sunday night clash has all the makings of a game that stays below the 42‑point total.

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