Houston Texans vs Tennessee Titans Prediction and Picks - November 16, 2025

By: Dean Whitaker Published 11/14/2025, 06:00 PM ET
Cam Ward looks to lead the Titans over the Texans
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Sunday afternoon on the NFL gridiron, and we have a Houston Texans vs Tennessee Titans prediction locked and loaded for you. The Texans enter this game off a 36-29 home win over Jacksonville to move to 4-5 on the year. The Titans are in the midst of a miserable -18 season, and they are off a 27-20 home loss to the Chargers. These teams met in Houston back in September, and the Texans won that game 26-0. Read on to see our Texans vs Titans prediction.

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Offense Explodes In Win Over Jags

The Texans enter Week 11 at 4–5, but they’re riding high after a wild 36–29 victory over Jacksonville, where they erased a 19-point deficit in the fourth quarter. With C.J. Stroud still sidelined in concussion protocol, Davis Mills stepped in and delivered, throwing for 292 yards and two touchdowns while keeping the offense steady. Wideout Nico Collins was the star, hauling in seven catches for 136 yards, and rookie back Woody Marks added balance with 63 rushing yards and a score. Houston’s offense has been streaky this season, but when they find rhythm, they can put points on the board quickly.

Offensively, Houston has averaged 22.7 points per game, leaning on a balanced attack that mixes the run and pass. Mills has shown he can manage the game effectively, and Collins has emerged as a reliable playmaker who can stretch defenses. The Texans’ offensive line has been inconsistent, but when they protect the quarterback, the passing game opens up. Against Tennessee, Houston will look to exploit a defense that has struggled to contain both the run and the pass, especially in late-game situations.

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Defensively, the Texans have been one of the league’s best units, allowing just 16.7 points per game and ranking first overall in yards allowed. Danielle Hunter has been a force up front, piling up sacks and disrupting opposing quarterbacks, while the secondary has held opponents to just 171 passing yards per game. Houston’s ability to pressure the quarterback and force turnovers has been the backbone of their success. Facing a Titans offense that ranks last in scoring, the Texans will aim to control the line of scrimmage and keep Tennessee’s young quarterback uncomfortable all afternoon.

The Long Season Continues For The Titans

The Titans come in at 1–8, and while they’ve shown flashes of competitiveness, they’ve struggled to finish games. Their most recent outing was a 27–20 loss to the Chargers, where rookie quarterback Cam Ward threw for 145 yards but failed to find the end zone. Running back Tony Pollard provided a spark with 56 rushing yards, and receiver Elic Ayomanor chipped in with 46 yards through the air. Still, the offense has been stuck in neutral, averaging just 14.4 points per game, the lowest mark in the league.

Offensively, Tennessee has been plagued by poor pass protection and a lack of consistency in the passing game. Ward has talent and mobility, but he’s been sacked more than any quarterback in the NFL, and the offensive line hasn’t given him time to develop plays. Pollard has been efficient when given touches, but the Titans haven’t been able to establish a steady ground game. Against Houston’s top-ranked defense, Tennessee will need to find creative ways to move the ball, whether through quick passes or misdirection runs, to avoid being overwhelmed.

Defensively, the Titans have been middling, allowing nearly 27 points per game and struggling to stop opponents in key moments. Injuries have played a role, with Jeffery Simmons and other key defenders missing time, leaving the unit vulnerable. The secondary has been serviceable, but without consistent pressure up front, opposing quarterbacks have had too much time to pick them apart. Against Houston, Tennessee’s defense will need to step up, especially in containing Nico Collins and slowing down the Texans’ balanced attack. If they can’t generate turnovers or control the trenches, it could be another long afternoon in Nashville.

Houston Texans vs Tennessee Titans Pick

Texans vs Titans Spread Pick

  • Tennessee +6 (1 Unit)

Backing the Titans +6 has some logic because despite their 1–8 record, they’ve been competitive in stretches and have kept several games within one score. Rookie quarterback Cam Ward has shown flashes of mobility and poise, and with Tony Pollard providing balance in the backfield, Tennessee has enough weapons to at least sustain drives. Playing at home gives them a boost, and divisional matchups often tighten up regardless of records. Against Houston, the Titans’ ability to slow the game down and lean on Pollard could help them keep things close.

Defensively, Tennessee has struggled overall, but they still have playmakers capable of disrupting Houston’s rhythm. If Jeffery Simmons and the front seven can generate pressure, it will force Davis Mills into quicker decisions and limit big plays to Nico Collins. The Texans’ offense has been inconsistent without C.J. Stroud, and if the Titans can capitalize on that with a few stops, they’ll have a chance to hang around. Covering the spread doesn’t require a win—just keeping the margin tight—and Tennessee has the tools to grind this into a competitive AFC South battle.

Texans vs Titans Over/Under Pick

  • Under 37 (3 Units)

The Under 37 makes sense here because both offenses have struggled to sustain drives, and neither team has shown much explosiveness. Houston is averaging just 22 points per game without C.J. Stroud, while Tennessee sits at the bottom of the league at 14.4 points per contest. The Texans’ defense has been elite, holding opponents under 17 points per game, and the Titans’ offensive line issues make it hard to see them breaking through. With Houston leaning on balance and Tennessee trying to grind possessions, this AFC South matchup projects as a slower, defensive battle that stays below the number.

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