Kansas City Chiefs vs Seattle Seahawks Picks and Predictions for Sunday, October 25, 2026
The Kansas City Chiefs have won their first five games and will try to make it six when they face the Seattle Seahawks on Sunday. The game is at Lumen Field in Seattle, with kickoff at 8:20 pm ET on NBC. Kansas City leads the AFC West at 5-0 and is coming off a 22-6 victory over the Chargers. Seattle is second in the NFC West with a 3-3 record. The Seahawks have lost two straight, including a 17-14 overtime defeat against Denver on Thursday. The Chiefs are unbeaten in two road games, while Seattle has gone 2-1 at home. Cash in a winner with our free NFL picks.
Kansas City Chiefs Playing Well on Both Sides
The Chiefs didn't give the Chargers much of a chance last Sunday. Los Angeles managed only six points, and Kansas City came away with a 22-6 victory. That followed a close 30-27 win in Las Vegas and a 24-10 victory against Miami. The Chiefs also scored 33 against Indianapolis and 31 against Denver earlier in the season. They've now scored 140 points in five games, while their opponents have managed 83. Kansas City has been particularly good at stopping the run, with opposing teams averaging just 88.8 rushing yards per game. The Chiefs are also allowing only 217.2 passing yards per outing.
Patrick Mahomes has completed 105 passes through five games, gaining 1,309 yards. Nine of those throws have gone for touchdowns, and he's been intercepted three times. Travis Kelce leads the receiving group with 299 yards, followed by Tyquan Thornton with 219 and Xavier Worthy with 206. But Kansas City's running game has been just as important. Kenneth Walker III is averaging 133.0 rushing yards per game and has already scored six times on the ground. He's carried the ball 106 times for 665 yards, including seven runs of at least 20 yards. Nick Bolton leads the Chiefs with 48 tackles, while L'Jarius Sneed has forced two fumbles.
Injuries: Jaylon Moore is questionable. Josh Simmons, Jared Wiley, Garrett Nussmeier and Diego Pounds are inactive.
Seattle Seahawks Coming Off Two Tight Losses
Seattle was one possession away in both recent losses. The Seahawks fell 32-29 to San Francisco, then went to Denver and lost 17-14 in overtime. Before that, they beat the Chargers 30-23. Seattle scores 24.7 points per game while allowing 20.3, and opponents gain just 237.3 yards per outing, the lowest figure in the league. The run defense allows only 96.0 yards per game, making Walker's matchup worth watching.
Jaxon Smith-Njigba has caught 49 passes for 717 yards and seven touchdowns. Sam Darnold has thrown seven touchdowns but also seven interceptions through five games. Drew Lock has added four touchdown passes without a pick in two appearances. Emanuel Wilson leads Seattle's rushing attack with 303 yards on 87 carries. On defense, Ernest Jones IV has 59 tackles and three sacks, while Julian Love has two interceptions. The Seahawks need that defense to keep Mahomes from finding big plays.
Injuries: Jadarian Price is on injured reserve. Elijah Arroyo is questionable. Jalen Milroe, Brandon Pili and Avery Smith are inactive.
Key To The Game
Kansas City averages 159.8 rushing yards per game, while Seattle allows just 96.0. That battle will affect how much Mahomes needs to throw. The Seahawks also need to protect the ball against a Chiefs defense allowing 16.6 points a game.
Kansas City Chiefs vs Seattle Seahawks Pick
- Kansas City Chiefs +2.5
Kansas City has won all five games, including two on the road, and its defense is giving up just 16.6 points per contest. Seattle has a strong defense too, but Darnold's seven interceptions create a concern against a team that rarely needs help scoring. Walker has been gaining 6.3 yards per carry, giving Mahomes another option. The Chiefs will stay unbeaten and cover the 2.5-point spread as road underdogs Sunday.
Kansas City Chiefs vs Seattle Seahawks Over/Under Pick
- Over 42.5
Seattle has played close games, but the Seahawks scored at least 29 points in three of their four games before the loss at Denver. Kansas City averages 28.0 points and has put up 30 or more twice this season. Walker can create long gains on the ground, while Smith-Njigba is difficult to contain through the air. Both teams have enough weapons for this game to finish over 42.5 points Sunday.