Los Angeles Chargers vs Los Angeles Rams Picks and Prediction for Sunday November 1, 2026
The Los Angeles Chargers will be in Inglewood, California, Sunday afternoon for a matchup against the Los Angeles Rams inside SoFi Stadium. The game is scheduled to begin at 4:05 PM ET, with FOX coverage. The Chargers come into Sunday winless at 0-6 overall following their bye week, looking to pick up their first victory of the season. The Rams return home at 3-4 overall after a double-digit win over the Raiders in their last outing. Los Angeles is a 6.5-point favorite at -278 on the money line. The Chargers are +225 on the money line, and the total is set at 45.5 points. Follow along with our NFL Picks.
Los Angeles Chargers desperate for any good news
Justin Herbert is leading the Los Angeles offense this season with 1,141 yards and five touchdowns on 107 completions. Omarion Hampton is the top ball carrier on the team with 289 yards and three scores on 80 carries this season. Tre Harris has compiled 225 yards on 15 receptions to lead Los Angeles. Ladd McConkey is second on the roster with 200 yards and one touchdown on 13 catches.
Defensively, Los Angeles was terrible in their last outing, giving up 422 yards and 22 points in the loss. Offensively, they were just as bad, compiling 259 yards and turning the ball over twice to score only six points in the game. Justin Herbert led the way for the Los Angeles offense, completing 22 passes for 204 yards and running the ball five times for 26 yards. Quentin Johnston led the team with 57 yards on one catch. KeAndre Lambert-Smith added 32 yards on five catches.
Key Injury Report for Los Angeles:
- Kayode Awosika (Out) - Lower Leg
- Deane Leonard (Out) - Concussion
- Donte Jackson (Questionable) - Hamstring
- Derwin James Jr. (Out) - Hamstring
- Brenen Thompson (Out) – Quad
Rams look to get things rolling
Matthew Stafford is leading the Los Angeles offense this season with 1,989 yards and 14 touchdowns on 187 completions. Kyren Williams is the top ball carrier on the team with 492 yards and five touchdowns on 96 carries. Blake Corum has added 64 carries for 316 yards and two scores. Puka Nacua is the top receiver on the team with 485 yards and two touchdowns on 45 catches. Davante Adams has chipped in 30 catches for 480 yards and four scores.
Offensively, Los Angeles was the better team a week ago, compiling 386 yards to score 35 points, including 28 in the first half. Defensively, Los Angeles did the work, giving up 21 points on 350 yards in the game. Matthew Stafford led the way for the Los Angeles offense last week, completing 23 passes for 195 yards and three scores. Kyren Williams led the way out of the Los Angeles backfield with 99 yards and one touchdown on 16 carries. Blake Corum added 93 yards and one score on 17 carries. Puka Nacua was the top target in the Rams offense with 68 yards and one touchdown on eight receptions. Davis Allen added 20 yards and two scores on four grabs.
Key Injury Report for Los Angeles:
- Trent McDuffie (Questionable) -Groin
- Jordan Whittington (Questionable) - Back
- Colby Parkinson (Questionable) - Rib
- Joe Cardona (Doubtful) - Ankle
- Coleman Shelton (Questionable) - Hip
Los Angeles Chargers vs Los Angeles Rams Picks and Prediction
Pick: Los Angeles Rams -6.5
The Rams are the better team coming into this matchup, and they should have enough offensive firepower to take advantage of a winless Chargers squad. The Chargers have struggled to finish games this season, and their defense could have problems slowing down the Rams' passing attack. Look for the Rams to establish their offense early and put pressure on the Chargers to keep pace. The Chargers should have some success offensively following their bye week, but the Rams have the advantage on both sides of the football and should pick up the victory.
Total Pick: Over 45.5
This matchup has the potential to turn into a high-scoring game because both teams have offensive weapons capable of creating explosive plays. The Rams should be able to move the football consistently against the Chargers, while the Chargers could find some success through the air if they are forced to play from behind. Both teams will have opportunities to put points on the board, and a faster pace in the second half could lead to additional scoring. Expect the Rams to control the game offensively while the Chargers contribute enough to push the final score higher.