New England Patriots vs Chicago Bears Picks and Prediction for Thursday October 22 2026

By: Kim Smith Published 10/22/2026, 01:04 AM ET

New England Patriots vs Chicago Bears Game Information

The New England Patriots will travel to Chicago on Thursday night for a matchup against the Chicago Bears at Soldier Field. Kickoff is scheduled for 8:15 PM ET, with television coverage available on Prime Video. New England enters the contest with a 4-2 record following a 26-19 victory over the New York Jets, extending its winning streak to three games. Chicago also enters at 4-2 after defeating the Atlanta Falcons 31-23 on Sunday afternoon. New England enters Thursday night as a slight underdog at +3 and +130 on the Money line. Chicago is a -3 and a -155. The total is currently 50.5. Stay in the action with our NFL Picks.

Patriots look to stay hot

Drake Maye is leading the New England offense this season with 1463 yards and 11 scores on 117 completions, along with 185 yards and one touchdown on 34 carries. Rhamondre Stevenson is the top ball carrier on the team with 263 yards and two touchdowns on 71 carries, and TreVeyon Henderson has added 194 yards and one score on 49 carries. Romeo Doubs is leading New England with 261 yards and three touchdowns on 14 receptions. DeMario Douglas has added 233 yards and three scores on 20 grabs, and Hunter Henry has chipped in 19 catches for 225 yards and two scores.

The New England offense was the better unit a week ago, compiling 383 yards to score 26 points, including 17 in the first half. Defensively, New England did have some trouble but did the work, giving up 19 points on 324 yards and forcing 1 turnover in the win. Drake Maye led the charge for New England last week, completing 18 passes for 235 yards and three scores. Corey Kiner led the way out of the New England backfield with 57 yards on 11 carries. DeMario Douglas led the team with 86 yards and one touchdown on 7 catches. Hunter Henry chipped in four catches for 48 yards on one score, while Romeo Doubs added 42 yards and one touchdown on one grab.

Key Injury Report for New England:

  • Morgan Moses (Questionable) -Foot
  • Channing Canda (Out) – Hamstring)Β 
  • Karon Prunty (Out)- Hamstring
  • Ben Brown (Out) -Knee
  • Alijah Vera-Tucker (Out) -Hamstring

Bears hunt 2 in a row

Caleb Williams is leading the Chicago offense this season with 712 yards and three touchdowns on 66 completions through three games played. Tyson Bagent has compiled 409 yards on 42 completions, and Case Keenum has chipped in 35 completions for 355 yards and two scores. D’Andre Swift led Chicago with 398 yards and six touchdowns on 94 carries. Kyle Monangai is second on the team with 324 yards and three scores on 60 carries. Luther Burden III is the top receiver this season with 361 yards and one score on 31 catches.

Chicago did the job on the offensive side a week ago against Atlanta scoring 31 points on 368 yards. Defensively, Chicago was shaky, giving up 23 points on 257 yards, including sixteen in the fourth quarter. Caleb Williams led the way for the Chicago offense, completing 30 passes for 305 yards and one score. Roschon Johnson was the top ball carrier of the team with 51 yards and one touchdown on 13 carries. D’Andre Swift added 16 carries for 44 yards and two scores.

Key Injury Report for Chicago:

  • Jack Sanborn (Out) - Concussion
  • Anthony Johnson Jr. (IR) -Undisclosed
  • Tyrique Stevenson Sr. (Questionable) – Hip
  • TJ Edwards (Doubtful) - Hamstring

New England Patriots vs Chicago Bears Picks and Prediction

Pick: Chicago Bears

Chicago returns home Thursday night looking to build on an impressive offensive performance against Atlanta. Caleb Williams returned to the lineup Sunday and immediately gave the Bears a boost, leading to 31 points. The Bears should have opportunities to move the football against a New England defense that’s struggled against the Jets. New England has won three consecutive games, and Drake Maye has been playing well, but the Patriots could have difficulty protecting their quarterback against Chicago's defensive front. Injuries along New England's offensive line are another concern, particularly with both teams playing on a short week. Chicago will need to establish its running game and avoid allowing Maye to extend drives with his arm. Look for the Bears to take advantage of playing at home and make enough plays offensively to secure the victory.

Pick: Over 50.5

Thursday night's matchup features two offenses that have shown significant improvement over the last several weeks. New England has scored at least 26 points in three consecutive games, including a 45-point performance against Las Vegas. Maye has been effective moving the football through the air, and the Patriots should have opportunities to attack a Chicago defense that surrendered 23 points against Atlanta last weekend. The Bears have also demonstrated their ability to produce offensively, particularly with Williams back under center. Chicago scored 31 points against Atlanta and should be able to establish a balanced attack with its passing game and rushing offense. Both quarterbacks have the ability to extend plays and create opportunities downfield, which could lead to several explosive possessions. With both teams entering the matchup playing well offensively, expect enough scoring opportunities to push this game over the posted total.

Final Picks

Winner: Chicago Bears

Total: Over 50.5

>

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.