New England Patriots vs. Tennessee Titans, Picks and Prediction, Sunday, October 19, 2025

By: Cole Shelton Published 10/17/2025, 05:47 PM ET
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The New England Patriots are on the road to play the Tennessee Titans on Sunday, October 19, at 1 p.m. ET in Week 7. New England (4-2) is coming off a 25-19 win over the New Orleans Saints. Tennessee (1-5) is coming off a 20-10 loss to the Raiders. Continue reading for our Patriots vs. Titans prediction.

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Patriots Atop AFC East

New England enters Week 7 with a record of 4-2 and is atop the AFC East. The Patriots are coming off a 25-19 road win over the Saints. In New England's last win, the Patriots were led by second-year quarterback Drake Maye, who threw for 261 yards and three touchdowns, while also rushing for 28 yards. Kayshoun Boutte led the way with 93 receiving yards and two touchdowns. Maye is completing 73.2% of his passes for 1,522 yards with 10 TDs and two picks on the season. He also has 138 rushing yards and two scores.

The Patriots are averaging 25 points per game. They are also averaging 244.5 passing yards per game and 91.5 rushing yards per game as the offense has been solid, backed by Maye and a resurgent passing game. New England's defense, meanwhile, is allowing 20 points per game, while opponents are averaging 250.66 passing yards and 83.5 rushing yards per game.

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Titans Fire Head Coach

After Tennessee suffered a 20-10 loss to the Raiders, the Titans fired head coach Brian Callahan and his father, Bill, who was the offensive line coach. Mike McCoy was named the interim head coach. In the loss to the Raiders, rookie quarterback Cam Ward threw for 222 yards, one touchdown and one interception. Tony Pollard led the ground game with just 34 rushing yards, as the offense has been an issue led by a poor offensive line. Ward has been sacked 25 times this season.

Overall, he's completing 55% of his passes for 1,101 yards with three TDs and four interceptions. Pollard leads the ground attack with 362 yards and two scores, while Calvin Ridley is the vertical threat with 16 catches for 290 yards.

The Titans are averaging 13.83 points per game while averaging just 183.5 passing yards and 81.83 rushing yards per game. Defensively, Tennessee has struggled as the Titans are allowing 26.83 points per game, 221.5 passing yards, and 133.66 rushing yards.

Patriots vs. Titans Pick

Spread pick for Patriots vs. Titans

  • Patriots -7 (-110) (5 units)

New England is a seven-point favorite and rightfully so, as the Patriots should cruise to a lopsided win here against a team that is in a bit of disarray after firing the Callahans. Patriots coach Mike Vrabel is making his return to Tennessee, so he should have New England fired up for this game to make a statement. The Pats defense has been stellar this season and should pose a lot of problems for Cam Ward, who has made some rookie mistakes and will likely turn the ball over. Maye, meanwhile, should be able to continue to find the deep ball and pick apart the Titans' defense for a lopsided win.

Over/Under pick for Patriots vs. Titans

  • Under 42.5 -110 (5 units)

The under is also a great spot here as Tennessee has struggled to put up many points, while the Patriots have a solid defense, which should make life difficult for the Titans' offense. Vrabel's defense will be in Ward's face all day making it difficult for him to get any passing game going. The Patriots are 4-2 in hitting the under this season, while Tennessee is 3-3. The Titans will struggle to move the ball and get many points, as the Pats should get a 24-14 win here for the under to cash.

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