New York Jets vs Detroit Lions Picks and Prediction for Sunday September 27 2026

The New York Jets visit the Detroit Lions at Ford Field in Detroit, Michigan, on Sunday, September 27, 2026. Kickoff is scheduled for 1:00 PM ET with coverage on CBS. New York enters at 1-1 after suffering a painful 20-17 overtime loss to Green Bay, while Detroit is also 1-1 after losing 41-31 at Buffalo on Thursday night. The Lions are currently favored by 6.5 points with a total of 47.5. Be sure to check out our free NFL picks for more NFL predictions throughout the season.

New York Has to Recover From a Missed Opportunity

The Jets had an excellent opportunity to move to 2-0 in Week 2. New York led Green Bay 17-7 with approximately 11 minutes remaining before allowing the Packers to come back and win 20-17 in overtime. Turning the page quickly will be important because another difficult opponent awaits in Detroit.

There were positives despite the loss. New York demonstrated that it can compete against a quality opponent and was in control for much of the afternoon. That makes the Jets more interesting as nearly a touchdown underdog than their Week 2 result alone might suggest.

The challenge will be avoiding the mistakes that allowed Green Bay back into the game. Detroit has enough offensive firepower to punish short fields and missed opportunities. New York needs to finish possessions and cannot allow another game to slip away because of late mistakes, penalties or special-teams issues.

Detroit Looks to Bounce Back at Ford Field

Detroit enters after a 41-31 loss at Buffalo. The Lions still generated 31 points on the road, which is encouraging offensively, but surrendering 41 highlights the defensive issues that make laying 6.5 points somewhat uncomfortable.

The Lions return home with additional rest following their Thursday night game. That scheduling advantage should provide more time to address the defensive problems that surfaced in Buffalo. Detroit does not necessarily need to completely fix those concerns to win, but the Lions need enough stops to prevent New York from hanging around into the fourth quarter.

Offensively, Detroit should have opportunities to attack. The Lions have already demonstrated that they can score even when playing from behind. If they establish the lead this time, the pressure will shift toward a Jets offense that failed to close out Green Bay despite holding a double-digit fourth-quarter advantage.

New York Jets vs Detroit Lions Picks and Prediction

Pick: New York Jets +6.5

The Jets +6.5 are the side pick. Detroit deserves to be favored at home, but the Lions just surrendered 41 points and New York was competitive enough to build a 17-7 fourth-quarter lead against Green Bay. Getting nearly a touchdown provides useful protection in a matchup where Detroit’s defense has not shown enough reliability to make a comfortable victory automatic.

Pick: Over 47.5

The Over 47.5 is the total pick. Detroit just participated in a 72-point game and scored 31 despite losing. New York has also demonstrated enough offensive capability to threaten the 20-point range. Detroit’s offense combined with its defensive vulnerability creates a reasonable path to something like 28-24 or 30-21.

Final Picks: New York Jets +6.5 and Over 47.5