Philadelphia Eagles vs Chicago Bears Picks and Prediction for Monday September 28 2026

The Philadelphia Eagles visit the Chicago Bears at Soldier Field in Chicago, Illinois, on Monday, September 28, 2026. Kickoff is scheduled for 8:15 PM ET with national coverage on ESPN. Philadelphia enters the matchup at 2-0 after opening the season with victories over Washington and Tennessee, while Chicago is 1-1 following a 9-3 home loss to Minnesota. The Eagles are currently listed as 3.5-point road favorites with the total set at 44.5. Philadelphia is around -185 on the moneyline, while Chicago is approximately +154. Be sure to check out our free NFL picks for more NFL predictions throughout the season.

Philadelphia Looks to Keep Its Perfect Start Going

Philadelphia has not been dominant through its first two games, but the Eagles have found ways to finish both of them. They opened with a 24-22 victory over Washington before escaping Tennessee with a 24-20 win. The second victory was particularly revealing because Philadelphia trailed late before putting together the decisive scoring drive. The Eagles are averaging 24.0 points through two games while allowing 21.0 per contest, so both victories have required them to execute in competitive fourth-quarter situations.

The Philadelphia offense has generated 659 total yards through two games, including 467 through the air and 225 on the ground. The passing attack has produced 233.5 yards per game and five touchdowns against two interceptions. The rushing production has been less impressive on a per-game basis, but Philadelphia continues to have enough offensive balance to prevent defenses from selling out against one dimension. Against Tennessee, the Eagles controlled possession for more than 36 minutes and ran 72 offensive plays, although two turnovers prevented them from creating more separation.

The biggest concern heading into Chicago is the health of the offense. Philadelphia is dealing with an important injury at tight end, which could alter some of the underneath passing concepts that have been part of the attack. Still, the larger matchup advantage may come from Philadelphia’s ability to remain patient. Chicago just played a low-scoring defensive game against Minnesota, so this may not be a situation where the Eagles simply race away early. Philadelphia’s ability to sustain drives and avoid giving Chicago short fields could determine whether the Eagles can create enough separation to cover the road number.

Chicago Tries to Rebound After Offensive Struggles

Chicago’s first two games could hardly have looked more different. The Bears exploded offensively in their opener, piling up points and yardage in a convincing victory, but they were held to only three points in the Week 2 loss to Minnesota. Chicago still generated 297 total yards and controlled possession for 32:41 against the Vikings, but two turnovers and an inability to finish drives prevented the Bears from reaching the end zone.

Through two games, Chicago has accumulated 849 total yards, including 461 passing yards and 425 rushing yards. That ground production is the most encouraging part of the early-season profile. The Bears have demonstrated the ability to create explosive rushing production and enter this matchup averaging 31.0 points per game despite scoring only three against Minnesota. The problem is that the Week 1 offensive explosion heavily influences that average, making the most recent performance particularly important when evaluating this matchup.

Quarterback availability is also a major variable for Chicago after the starter suffered a hamstring injury against Minnesota. The Bears were unable to generate a touchdown after the injury, and the offense became considerably easier to defend late in the game. Chicago’s rushing attack gives it a potential avenue to remain competitive regardless of who handles the quarterback duties, but playing from behind would create a much more difficult game script. The Bears need to keep Philadelphia from building an early two-score advantage and turn Monday night’s matchup into the type of possession-by-possession contest they played against Minnesota.

Philadelphia Eagles vs Chicago Bears Picks and Prediction

Pick: Philadelphia Eagles -3.5

Philadelphia has not produced a blowout through its first two games, but the Eagles have demonstrated a higher floor and have already won twice in close situations. Chicago’s rushing production deserves respect, especially at Soldier Field, but the uncertainty surrounding the Bears’ quarterback situation makes it difficult to trust Chicago against an undefeated Philadelphia team. The Eagles should be able to put more pressure on Chicago to sustain drives than Minnesota did, and Philadelphia has enough offensive balance to gradually create separation. At -3.5, the Eagles are the side.

Pick: Under 44.5

The under is the stronger total angle if Chicago again has difficulty generating explosive passing plays. Minnesota held the Bears to three points last week, and Chicago may emphasize its running game in an attempt to protect the quarterback position and shorten the contest. Philadelphia has scored exactly 24 points in each of its first two games rather than producing an offensive explosion, and the Eagles have shown they are comfortable winning without playing at a frantic pace. A game in the neighborhood of 24-17 or 27-14 would put Philadelphia in position to cover while keeping the combined score beneath 44.5.

Final Picks: Philadelphia Eagles -3.5 and Under 44.5