Seattle Seahawks vs Denver Broncos Picks and Prediction for Thursday October 15, 2026
The Seattle Seahawks will travel to Denver, Colorado, Thursday night for a Week 6 NFL matchup against the Denver Broncos at Empower Field at Mile High. Kickoff is scheduled for 8:15 PM Eastern with coverage available on Prime Video. Seattle enters the contest with a 3-2 record following a disappointing 32-29 loss against the San Francisco 49ers. The Seahawks will look to bounce back after committing four turnovers in that defeat and regain momentum on the road. Denver also enters the matchup at 3-2 after picking up a 23-17 road victory against the Los Angeles Chargers. The Broncos will attempt to build on that performance and use their home-field advantage against a Seattle team playing on a short week. Seattle is listed as a 2.5-point favorite, with the total set at 40.5 points.
Seattle goes for a bounce-back win
Sam Darnold is leading the Seattle offense this season with 755 yards and seven scores on 63 completions, and he has used his legs for five carries and 16 yards. Emmanuel Wilson is the top ball carrier on the roster with 251 yards and two touchdowns on 73 carries. Jadarian Price has added 119 yards on 28 carries, and George Holani is third on the roster with 77 yards on 26 carries. Jaxon Smith-Njigba leads all Seattle receivers this season with 583 yards and seven scores on 37 grabs. Cooper Kupp is second on the roster with 129 yards and one score on 11 catches, and AJ Barner has added 12 catches for 122 yards.
Offensively, Seattle moved the ball well last week, compiling 251 total yards to score 29 points but converted just three third downs and turned the ball over 4 times in the loss. Defensively, Seattle was outmatched, giving up 32 points, including 21 in the first half, on 269 total yards. Sam Darnold led the show for the Seattle offense last week, completing 18 passes for 195 yards and one score. Emmanuel Wilson was the top ball carrier on the team with 61 yards and one touchdown on 20 carries. Jaxon Smith-Njigba led the team with 102 yards and one touchdown on five receptions.
Key Injury Report for Seattle:
- Zach Charbonnet (PUP-R) - Knee-ACL Oct 25
- Drake Thomas (Out) - Ankle Oct 25
- Cahazz Surratt (Out) - Calf Oct 25
- Drew Lock (Questionable) - Forearm Oct 15
- Leonard Williams (Questionable) - Ankle Oct 15
Denver looks to cash the plus money
Bo Nix is leading the Denver offense this season with 942 yards and six touchdowns on 97 completions, along with 35 yards and one touchdown on 18 carries. JK Dobbins leads all Denver running backs with 229 yards and one touchdown on 64 carries. Jaylen Waddle is the top receiver on the team with 204 yards and one touchdown on 18 catches. Pat Bryant has chipped in heavily with 133 yards and one score on 9 catches. Evan Engram has added 10 catches for 121 yards and one score, and Courtland Sutton has chipped in 11 catches for 104 yards and one touchdown. Nate Adkins has four catches for six yards and two scores.
The Denver defense was a better unit a week ago, giving up 17 points on 237 total yards, and they forced 3 turnovers in the game. Offensively, Denver found a way, scoring 23 points, including thirteen in the fourth quarter, on 224 total yards. Bo Nix led the Denver offense last week, completing 16 passes for 123 yards and one score. JK Dobbins led the way out of the backfield with 68 yards and one touchdown on 18 carries. Evan Engram boasted a team-high 55 yards on 4 catches. Courtland Sutton had 18 yards and one score on 2 catches.
Key Injury Report for Denver:
- Pat Surtain II (Out) - Ankle Oct 25
- Talanoa Huganga (Out) - Ankle Oct 25
- Riley Moss (Questionable) - Ribs Oct 15
- Pat Bryant (IR) - Ankle November 8
••Jonah Coleman (IR) - Ankle Oct 25
Seattle Seahawks vs Denver Broncos Picks and Prediction
Pick: Seattle Seahawks -2.5
Seattle has an opportunity to bounce back Thursday night against a Denver team that has struggled to produce consistent offense through the opening five games. The Seahawks have been the more productive offensive team, and Jaxon Smith-Njigba gives Sam Darnold a dangerous receiving option capable of creating separation and generating explosive plays. Denver's defense will present a challenge, particularly if the Broncos establish pressure and force Darnold into difficult throws. However, Seattle should be able to create opportunities by getting the ball out quickly and attacking favorable matchups in the secondary. The Seahawks must also protect possession after their turnover-filled loss to San Francisco. If Seattle avoids giving Denver short fields and forces Bo Nix to sustain long scoring drives, the Seahawks should have enough offensive firepower to win on the road.
Pick: Under 40.5
Seattle and Denver enter Thursday's matchup with defenses capable of making life difficult for opposing quarterbacks, and the short turnaround could further limit offensive execution. The Seahawks have been effective at defending opposing passing attacks, while Denver has also demonstrated an ability to limit production through the air. Both offenses could struggle to consistently convert third downs, resulting in shorter possessions and fewer sustained scoring drives. Denver should attempt to establish its running game to keep Seattle's offense off the field, while the Seahawks will need to remain patient against a defense capable of generating pressure. With both teams facing difficult defensive matchups and limited preparation time, sustained scoring could be difficult. Expect a physical contest with field position playing an important role.