Chicago Blackhawks vs Buffalo Sabres Prediction and Picks - November 21, 2025
Use Code SSWC National Hockey League action on Friday evening, and we have a Chicago Blackhawks vs Buffalo Sabres prediction ready to rock and roll. The Blackhawks come in off a 3-2 home loss to Seattle to fall to 10-10 on the year. Buffalo has gone 7-13 on the year and they are off a 6-2 home loss to Calgary. Buffalo won all four meetings last year. Read on to see our Blackhawks vs Sabres prediction.
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Blackhawks Blow Two-Goal Lead Vs Seattle
Chicago’s most recent game was a tough one at the United Center last night, where they let a two-goal lead slip away in the third period and fell 3-2 to the Seattle Kraken. Tyler Bertuzzi and Teuvo Teravainen each scored in the second period to put the Hawks up 2-0, but Seattle stormed back with three unanswered goals in the final frame, capped by Jaden Schwartz’s power-play winner. Spencer Knight made 24 saves, but Chicago’s six-game point streak came to an end.
Despite the loss, the Blackhawks have been one of the more surprising teams in the league this season. Connor Bedard continues to shine with 29 points in 20 games, while Bertuzzi has chipped in 17 points and four power-play goals. Depth scoring has come from Frank Nazar (14 points) and Ryan Donato (12 points), and the power play has been a weapon at 24.1% efficiency, ranking ninth in the NHL. Chicago averages 3.3 goals per game, good for seventh overall, and their offensive balance has kept them competitive against stronger opponents.
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Defensively, Chicago has been stout, allowing just 2.5 goals per game, the third-best mark in the league. Arvid Soderblom will get the start against Buffalo, bringing a 2.52 GAA and .912 save percentage into the matchup. The penalty kill has also been strong at 83.6%, and the Hawks’ ability to limit high-danger chances has been a key factor in their early success. Against Buffalo, Chicago will look to rebound quickly, leaning on Bedard’s playmaking and a disciplined defensive structure to get back in the win column.
Buffalo Gets Torched By The Flames
Buffalo’s last outing came on November 19, when they were overwhelmed at home in a 6-2 loss to the Calgary Flames. The Sabres scored twice in the second period—one from Tage Thompson and another from Mattias Samuelsson—but the Flames erupted for four goals in the third to put the game out of reach. Ukko-Pekka Luukkonen allowed six goals on 31 shots, and Buffalo’s defensive lapses proved costly in front of the KeyBank Center crowd.
The Sabres’ offense has been inconsistent, averaging 2.9 goals per game. Thompson leads the team with 18 points, while Alex Tuch has chipped in 16 and Zach Benson has impressed with eight assists in just eight games. Depth contributions have come from JJ Doan (12 points) and Bowen Byram (9 points), but Buffalo’s power play has struggled at just 16.4%. Faceoff issues (42.6%) have also left them chasing possession far too often, limiting their ability to sustain pressure.
Defensively, Buffalo has been shaky, giving up 3.5 goals per game, ranking 28th in the NHL. The bright spot has been their penalty kill, which sits first overall at 89.8%, thanks to strong work from Dahlin and Samuelsson on the back end. Luukkonen will get the start against Chicago, and while his numbers (3.01 GAA, .883 save percentage) reflect the team’s defensive struggles, he’s capable of stretches of solid play. Facing a Blackhawks team that thrives on offensive bursts, Buffalo will need its top scorers to step up while tightening up defensively to avoid another lopsided defeat.
Chicago Blackhawks vs Buffalo Sabres Pick
Blackhawks vs Sabres Moneyline Pick
- Buffalo -1.5 (2 Units)
Buffalo -1.5 is a logical angle given the scheduling spot. Chicago is coming in on the second night of a back-to-back after a draining loss, and while the Blackhawks have been competitive this season, fatigue often shows up in defensive lapses and special teams execution. Buffalo, meanwhile, has the benefit of rest and home ice, and their penalty kill has been elite at 89.8%, the best mark in the league. With Tage Thompson and Alex Tuch driving the offense, the Sabres have the firepower to take advantage of a tired opponent and push the pace.
The matchup also favors Buffalo’s ability to generate offense late in games. Chicago’s defense has been strong overall, but their shot suppression is shaky, ranking 29th in shots allowed per game. That opens the door for Buffalo’s forwards to pepper Arvid Soderblom, who is starting in net, and wear down a defense that logged heavy minutes just 24 hours earlier. If the Sabres can get an early lead, the combination of rested legs and Chicago’s fatigue should tilt the ice in Buffalo’s favor, making the puck line a realistic play.
Blackhawks vs Sabres Over/Under Pick
- Over 6 (3 Units)
The Over 6 looks appealing because both teams bring contrasting strengths that can still push the total higher. Chicago has been efficient offensively, averaging 3.3 goals per game with Connor Bedard driving play and a power play clicking at 24.1%. Buffalo, while inconsistent, still averages 2.9 goals per game and has top-line talent in Tage Thompson and Alex Tuch capable of breaking open a game. Defensively, the Sabres have struggled, allowing 3.5 goals per game, while Chicago is coming off a back-to-back that could expose their normally strong defense. With tired legs on one side and shaky coverage on the other, this matchup sets up for enough scoring chances to push past the number.
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