Colorado Avalanche vs. Buffalo Sabres Picks and Prediction for Monday, October 13, 2025

By: Justin Walker Published 10/13/2025, 01:04 AM ET
Colorado Avalanche vs. Buffalo Sabres Picks and Prediction
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Get ready for a nonconference NHL showdown as the Colorado Avalanche, standing in first place of the Central Division with a 2-0-1 record, clash with the Atlantic Division’s eighth-place Buffalo Sabres, who bring a 0-2-0 record into the fray. Set in the heart of the KeyStone Center on October 13th at 12:30 PM ET, fans can catch the action live on ESPN+. This will be the first of two games against one another as they will play in exactly one month as well. Hit the ice with confidence! Stay out of the box: NHL predictions for Colorado Avalanche vs. Buffalo Sabres, crisp and clear.

Avalanche Looking to Roll

The Colorado Avalanche, positioned in first place in the Central Division with a 2-0-1 record, head into this game winning two of their first three games heading into this matchup. The latest game against the Dallas Stars at home in a shootout 5-4 was a loss, but should feel good that they overcame a one-goal deficit in the third period to still get a point.

 

Offensively, Colorado has been doing a decent job at finding the back of the net, averaging 3.33 goals per game, which is tied for 14th in the sport. Their offensive attack has shown up lately, though, as they have scored seven goals in their last two games. The Avalanche’s power play has been at a middling level, converting at a 20.0% clip, meaning there is a chance for this offense to be even better. Their defensive game shows they are going to be in an excellent position, conceding an average of 2.00 goals against per game, highlighting an area of comfort at this point of the season.

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On the goaltending front, goaltender Scott Wedgewood is going to need to step up in the net for this game and is 2-0-1 with a .925 save percentage and 1.95 goals per game given up. As Colorado prepares to face Buffalo, the team needs to figure out how to avoid this being a trap game.

Injury Report for Colorado

  • Goalie Mackenzie Blackwood: Lower Body (Questionable)
  • Defenseman Samuel Girard: Upper Body (OUT)
  • Right winger Logan O’Connor: Hip (OUT)
  • Defenseman Jacob McDonald: Hip (OUT)
  • Defenseman Ronnie Attard: Lower Body (OUT)
  • Defenseman Sean Behrens: Undisclosed (OUT)
  • Center Nikita Prishchepov: Undisclosed (OUT)

Sabres Looking for Their First Points

The Buffalo Sabres, playing at a poor level up to this point as they are in last place in the Atlantic Division with a 0-2-0 record, face a team that is playing at an outstanding level so far this season. Their recent game on the road against the Bruins, a 3-1 loss, reflects a team that can just struggle to find the back of the net. Left winger Jason Zucker is leading the franchise with one point (one goal, zero assists). The Sabres are navigating through with six players on the injury report, and all but one of them are already ruled out for this game.

Buffalo’s offensive output has been terrible thus far, with the team sitting in last place in the league for goals scored, averaging just 0.50 goals per game. The Sabres’ power play, operating at a 0.0% success rate, and their penalty kill at 100.0%, highlight areas of the game that are hit-and-miss for them in the early stages of the season.

Goaltending is one of the team’s biggest positions of strength, with Alex Lyon doing a good job this year as he is 0-2-0 with a .919 save percentage and 2.55 goals allowed per game.

Injury Report for Buffalo

  • Left winger Zach Benson: Face (Questionable)
  • Center Joshua Norris: Upper Body (OUT)
  • Goalie Ukko-Pekka Luukkonen: Lower Body (OUT)
  • Defenseman Michael Kesselring: Undisclosed (OUT)
  • Left winger Jordan Greenway: Lower Body (OUT)
  • Right winger Carson Meyer: Knee (OUT)

Colorado Avalanche vs. Buffalo Sabres Pick

Spread Pick for Avalanche vs. Sabres

  • Colorado Avalanche -155 (5 units)

This is a game between the haves and the have-nots, so choose the haves to be victorious. The only issue is that this could be a bit of a game where the Avalanche takes their foot off the gas, but the Sabres have been unable to score much of anything, with only one goal in two games. Colorado has looked excellent on the ice and should be able to step up enough to win as Scott Wedgewood does not allow many goals to be scored against him. All in all, go with the Colorado Avalanche to continue picking up points with a road win across the country.

Over/Under Pick for Avalanche vs. Sabres

  • Under 6.5 (4 units)

This is going to be an interesting side bet to make as these defenses have not allowed much of a crooked number this season. Colorado is coming off a game where they allowed four goals, but Dallas is one of the most prolific offenses in the NHL, while Buffalo is on a completely different level there. The Avalanche have been an exciting offense, but there needs to be more to feel like this total is attainable. Wedgewood and Lyon have been able to limit the amount of times the puck finds the back of the net against them, so go with under 6.5 total goals to be scored here.

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