Ottawa Senators vs. Buffalo Sabres, Picks and Predictions, Wednesday, October 15, 2025

By: Anthony Leute Published 10/15/2025, 03:15 AM ET
Senators versus Sabres Prediction
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The Senators are traveling to the KeyBank Center in Buffalo, New York, for their matchup against the Sabres; keep reading for our Senators versus Sabres prediction. Ottawa is sixth in the Atlantic Division with a record of 1-2-0. Buffalo is last in the Atlantic Division with a record of 0-3-0. The Sabres had a record of 4-0-0 versus the Senators in 2024-25. The puck drop is scheduled for 7:00 p.m. EDT. Nobody does it better when it comes to NHL picks!

Senators Struggling In Net

The Senators are traveling to Buffalo after their loss on Monday against the Predators with a final score of 4-1. This would be the first loss of the season at home as the Senators would fall in their home opener. Ottawa will look to bounce back after their recent two crushing defeats with a win on the road against Buffalo.

Last season, the Senators ranked eighth in the league in save percentage at .901. However, to start this season, the Senators have been unable to reproduce this quality in net. We are seeing another season with Linus Ullmark in the net for the Senators, but so far this season, he has been struggling in his few starts. Ullmark has a goals against average of 4.07 in their first three games with a save percentage of only .842. To reach the postseason again, the Senators will need to fix this issue in net.

We will likely see Linus Ullmark get the start in net for the Senators on Wednesday

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Linus Ullmark:

  • had a record of 25-14-3 in 44 games with a goals against average of 2.72 and a save percentage of .909 in 2024-25.
  • has a 4-3-0 record in 7 games with a goals against average of 2.61 and a save percentage of .918 versus the Sabres in his career.

Injuries:

  • Tkachuk LW Day To Day - Wrist
  • Batherson RW Day To Day - Upper-body

Sabres Unable To Produce Goals

The Sabres picked up another loss on Monday versus the Avalanche with a final score of 3-1. This would be the third loss in a row for the Sabres, as they have yet to find a win this season. Buffalo continues a three-game home stand but has been unsuccessful in their first two games at home this season.

Buffalo is struggling on offense this season as they have only one goal across their first three games played. The lack of goal scoring is not from their lack of shots but rather their lack of quality, sitting last in the league currently in shooting percentage at 2.3%. To combat their poor offense, the Sabres have attempted to keep their games close thanks to their defense and goaltending, but it has not been enough due to Buffalo being unable to produce even one goal in their games. Last season, the Sabres ranked 10th overall in scoring but struggled when it came to allowing goals. Buffalo will need to focus on their offense if it wishes to capitalize on their successful defense.

We will likely see Alex Lyon start in the net for the Sabres on Wednesday.

Alex Lyon:

  • had a record of 14-9-1 in 30 games with a goals against average of 2.81 and a save percentage of .896 in 2024-25 with the Red Wings.
  • is 1-1-1 in 6 games with a goals against average of 3.69 and a save percentage of .901 against the Senators in his career.

Injuries:

  • Benson LW Day To Day - Face
  • Norris C Out - Upper Body
  • Luukkonen G Out - Lower-body
  • Kesselring D Out - Undisclosed
  • Greenway LW Out - Lower-body
  • Meyer RW Out - Knee

Senators vs. Sabres Picks and Predictions

Money Line Pick for Senators vs. Sabres

  • Sabres Money Line (4 units) 

The Sabres are 7-2-0 in their last nine games versus the Senators. Linus Ullmark has a 0-2-0 record in 2 games with a goals against average of 4.62 and a save percentage of .836 for the Senators versus the Sabres in his career. Neither team has looked great on offense this season but Buffalo may be able to find the goal-scoring game they need in their matchup against Ottawa. Ullmark has been struggling in net for the Senators this season and in his history against Buffalo with the Senators, it has not looked much better. Buffalo is desperate to score goals and bounce back after their three previous losses and this is the game where they do it.

Over/Under Pick for Senators versus Sabres

  • Over ( 4 units) 

The Sabres had an over/under record of 8-4-1 against the Atlantic Division at home in 2024-25. While taking the over in a Buffalo game may seem weird, we should see the Sabres produce more goals in this game than they have thus far this season. Buffalo is facing off against a struggling goaltender and they alone could take us close to the over. Buffalo is not perfect on defense and will likely allow a couple of goals to the Senators which will be enough to take us over the line. So far this season, the Sabres' power play has been nonexistent but they will be facing off against a struggling Ottawa penalty kill, which should allow for more goal-scoring opportunities than they have had in their first three games.

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