Best Touchdown Props NFL Week 16 - Weekly Player Props

NFL Anytime Touchdown Props Predictions and Picks for Week 16!

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NFL Week 16 Touchdown Props Prediction: James Cook Buffalo Bills (-125)

James Cook snapped a two-game touchdown drought with a season high three touchdowns last week as they Buffalo Bills offense rolled over the New England Patriots.

Cook has scored in 57% of his games on the season and the books are expecting a heavy workload this week in Cleveland as his rush attempts line is set at 19.5 and his rush yards line is set at 88.5.

The Cleveland Browns defense hasn’t been nearly as effective in recent weeks as they have allowed 31 points in back-to-back games against Chicago and Tennessee.

The Browns defense is also banged up with Denzel Ward & Carson Schwesinger listed as questionable, but they have really missed defensive tackle Maliek Collins in stuffing the run.

Collins is on the IR and in two games without him Cleveland let D’Andre Swift run for 98 yards & 2 TDs (Monangai 33 same game) and Tony Pollard run for 161 yards & 2 TDs.

Cook is tied for 3rd in the NFL for red zone rush attempts with 48 and he’s seen a combined 19 attempts in his last three games alone.

It will be cold with a chance of rain in Cleveland on Sunday afternoon which is a perfect recipe to keep pounding the rock.

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NFL Week 16 Touchdown Props Prediction: Bryce Young Carolina Panthers (+650)

We cashed a +300-longshot ticket on Tony Pollard in Week 15 so let’s see if we can catch lightning in a bottle and predict Bryce Youngs first touchdown since Week 3 of the 2025 campaign at +650 odds.

Young surprisingly only has one touchdown in 2025 after logging 6 during the 2024 season but he proved he isn’t afraid to run as he set season highs in rush attempts (7) and rush yards (49) last week.

The Tampa Bay Buccaneers have allowed the 2nd most quarterback rushing touchdowns with 6 on the season.

Kirk Cousins didn’t run last week but Tyler Shough ran for 55 yards & two scores against the Bucs two weeks ago and Josh Allen ran for 40 yards and 3 touchdowns in Week 11.

This is a critical game between NFC South rivals, and this is where we see quarterbacks play some hero ball and run more often.

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